Stereoselective ROMP Catalysts for Syndiotactic Polydicyclopentadiene

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Solution Overview

Problem

Current methods struggle to produce polymers with high stereoregularity, particularly highly syndiotactic poly(dicyclopentadiene) and hydrogenated poly(dicyclopentadiene), due to challenges in controlling the stereoselectivity of ring-opening metathesis polymerization of reactive monomers like endo-dicyclopentadiene.

Innovation Solution

The development of well-defined tungsten and molybdenum alkylidene complexes for ring-opening metathesis polymerization (ROMP) that promote stereoselective polymerization, achieving high syndiotacticity and cis-configured poly(dicyclopentadiene) and its hydrogenated forms, with specific metal complexes like compound 5 and 12 enabling rapid and controlled polymerization.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If conventional catalysts are used for ROMP of endo-dicyclopentadiene, then polymerization can proceed, but high stereoregularity and syndiotacticity cannot be achieved

Engineering Contradiction:
ImprovestereoregularityVSAvoidcatalyst design complexity
Core Design Contradiction:
Manufacturing precisionVSEase of manufacture

Solution Approach 1:

The patent applies local quality by designing catalysts with specific localized structural features - particularly the combination of oxo group and aryloxide group in the ligand system - that create a chiral environment at the metal center. This localized structural arrangement provides the stereoselectivity needed for syndiotactic polymerization without requiring complete redesign of the entire catalyst system.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent employs parameter changes by systematically varying ligand structures (different aryloxide groups, oxo vs imido combinations) and metal centers (tungsten, molybdenum) to optimize stereoselectivity. The specific choice of W(O)(CHCMe2Ph)(OHMT)2 represents an optimized parameter set that achieves high syndiotacticity while maintaining catalytic activity.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If highly reactive monomers like endo-dicyclopentadiene are polymerized, then rapid polymerization occurs, but control over stereoselectivity is lost

Engineering Contradiction:
Improvepolymerization rateVSAvoidstereoselectivity control
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent applies preliminary action by pre-organizing the catalyst structure with rigid ligand frameworks (OHMT, OiPrDT groups) that establish a predetermined chiral environment before monomer coordination. This pre-established structural arrangement guides the stereoselective insertion of reactive monomers, allowing rapid polymerization to proceed with high stereocontrol.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent utilizes asymmetry through the chiral ligand design - specifically the asymmetric arrangement of oxo and aryloxide groups around the metal center creates a chiral pocket that discriminates between enantiotopic faces of the monomer. This asymmetric environment is maintained throughout polymerization, enabling syndiotactic selectivity even with highly reactive monomers.

Inventive Principle:
Principle #4Asymmetry

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for the production of polymers with unprecedented high syndiotacticity and cis-selectivity, overcoming previous difficulties in achieving these configurations, and results in polymers with improved structural control and thermal properties, such as high melting points.

Implementation Method 1

ring-opening metathesis polymerization (ROMP) that promote stereoselective polymerization, achieving high syndiotacticity and cis-configured poly(dicyclopentadiene)

Methodology Applied
Scientific EffectRing-opening metathesis polymerization (ROMP): Chemical Bonding

Implementation Method 2

The development of well-defined tungsten and molybdenum alkylidene complexes for ring-opening metathesis polymerization (ROMP) that promote stereoselective polymerization

Methodology Applied
Scientific EffectCatalysis: Catalysis

Data Source

PatentEP3107655B1Catalysts and methods for ring opening metathesis polymerization
Publication Date: 2024.05.08 MASSACHUSETTS INST OF TECH
  • EP3107655B1 patent drawingFigure 1~2
  • EP3107655B1 patent drawingFigure 3
  • EP3107655B1 patent drawingFigure 4

AI summary

The present invention, among other things, provides highly syndiotactic poly(dicyclopentadiene) and/or hydrogenated poly(dicyclopentadiene), compositions thereof, and compounds and methods for preparing the same. In some embodiments, a provided compound is a compound of formula I, II or III. In some embodiments, a provided method comprises providing a compound of formula I, II or III.