Strontium-Doped Root Canal Filling Paste With Faster Setting and Bonding

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Solution Overview

Problem

Existing strontium-doped root canal filling pastes suffer from long curing times, low strength, and insufficient bonding with the root canal wall, despite previous improvements through chemical doping of calcium silicate compounds with strontium.

Innovation Solution

A strontium-doped root canal filling paste is prepared by physically mixing calcium silicate and strontium compounds, along with radiation inhibitors, calcium phosphate compounds, and organic solvents, to form a paste that is then ball-milled and mixed uniformly, enhancing mineralization, biological activity, and bonding strength.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If chemical doping method is used to incorporate Sr into calcium silicate lattices, then some properties are improved, but setting time becomes long, mineralization property is insufficient, and bonding strength with root canal wall is poor

Engineering Contradiction:
Improvebiocompatibility and antibacterial propertyVSAvoidsetting time
Core Design Contradiction:
ReliabilityVSDuration of action of moving object

Solution Approach 1:

The patent changes the doping method from chemical substitution to physical mixing, and optimizes the Sr content parameter to 0.5%-10% of total mass, which significantly shortens setting time while maintaining biocompatibility and antibacterial properties

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite material system combining calcium silicate compound and strontium compound through physical doping, achieving synergistic effects that improve both setting time and biological properties simultaneously

Inventive Principle:
Principle #40Composite materials

2Reliability

If chemical doping method is used to incorporate Sr into calcium silicate lattices, then some properties are improved, but mineralization property remains insufficient

Engineering Contradiction:
ImprovebiocompatibilityVSAvoidmineralization property
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent optimizes the Sr content parameter within 0.5%-10% range and uses physical doping instead of chemical substitution, which significantly enhances mineralization property while maintaining biocompatibility

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The strontium compound acts as an intermediary that promotes mineralization by releasing Sr ions that stimulate osteoblast activity and bone formation, achieving better mineralization than chemical doping

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If chemical doping method is used to incorporate Sr into calcium silicate lattices, then some properties are improved, but bonding strength with root canal wall is poor

Engineering Contradiction:
ImprovebiocompatibilityVSAvoidbonding strength with root canal wall
Core Design Contradiction:
ReliabilityVSStrength

Solution Approach 1:

The patent changes the doping approach to physical mixing and optimizes Sr content to 0.5%-10%, which significantly improves bonding strength with root canal wall while preserving biocompatibility

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces chemical bonding mechanisms with physical mixing and ion release mechanisms, allowing Sr ions to enhance bonding through biological activity rather than chemical lattice substitution

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Reliability

If conventional MTA is used, then biocompatibility and antibacterial property are good, but mixing is troublesome and wasteful

Engineering Contradiction:
Improvebiocompatibility and antibacterial propertyVSAvoidease of use
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent pre-mixes calcium silicate compound with strontium compound and organic solvent to form a ready-to-use paste before clinical application, eliminating the need for mixing at the site and reducing waste from partial-use scenarios

Inventive Principle:
Principle #10Preliminary action

5Ease of operation

If premixed paste with organic solvent is used, then ease of use is improved, but setting time becomes long and treatment period is extended

Engineering Contradiction:
Improveease of useVSAvoidsetting time
Core Design Contradiction:
Ease of operationVSDuration of action of moving object

Solution Approach 1:

The patent optimizes the Sr content parameter to 0.5%-10% and uses physical doping method, which significantly accelerates setting reaction while maintaining ease of use as a premixed paste

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The physical doping method significantly shortens curing time, improves bonding strength with the root canal wall, and enhances mineralization properties, resulting in better sealing and biological activity.

Implementation Method 1

the component (a) and the component (b) are doped in a physical doping manner

Methodology Applied
Scientific EffectPhysical doping:

Implementation Method 2

the raw materials are ball-milled to form a mixed powder

Methodology Applied
Scientific EffectBall-milling:

Implementation Method 3

enhancing mineralization, biological activity, and bonding strength

Methodology Applied
Scientific EffectMineralization:

Implementation Method 4

improves bonding strength with the root canal wall

Methodology Applied
Scientific EffectBonding: Adhesive

Data Source

PatentEP4643842A1Strontium-doped root canal filling paste, preparation method therefor and use thereof
Publication Date: 2025.11.05 GUILIN KEVIN PETER TECHNOLOGY CO LTD
  • EP4643842A1 patent drawingFigure 1~2
  • EP4643842A1 patent drawing
  • EP4643842A1 patent drawing

AI summary

The present application relates to the technical field of medical materials, and specifically to a strontium-doped root canal filling paste, a preparation method therefor and use thereof. Raw materials of the strontium-doped root canal filling paste include a component (a) and a component (b), wherein the component (a) is selected from calcium silicate compounds, the component (b) is selected from strontium compounds, the component (a) accounts for 20%-40% of a total mass of the raw materials, the component (b) accounts for 0.5%-10% of the total mass of the raw materials; and the component (a) and the component (b) are doped in a physical doping manner. The strontium-doped root canal filling paste can simultaneously address the problems of long curing time, low strength, bad mineralization property and insufficient effect of bonding with a root canal wall of the existing strontium-doped root canal filling paste.