Rotary Dial Pin Assemblies for Microwell Plate Transfer
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Solution Overview
Problem
Existing automated machines for transferring solutions between microwell plates are cumbersome and expensive, lacking efficiency and flexibility in handling various transfer modes and volumes.
Innovation Solution
An automated machine with a rotatable circular dial and pin assemblies that can move solution between microwell plates, controlled by a computer for precise solution transfer, cleaning, and customizable operations, including variable volume transfers and array printing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Extent of automation
If prior art machines are used for transferring solution between microwell plates, then solution transfer can be automated, but the machines are cumbersome and expensive
Solution Approach 1:
The device is divided into modular components: a rotatable dial with multiple pin assemblies, each pin being an independent transfer unit. This segmentation allows the complex function of plate-to-plate transfer to be broken into simple, repeatable pin movements, reducing overall system complexity while maintaining automation
Solution Approach 2:
The pin assemblies serve multiple functions: they can transfer solution between plates, clean themselves by dipping into wash wells, and be sterilized by autoclaving. This multi-functionality reduces the need for separate cleaning and sterilization systems, thereby reducing device complexity
2Extent of automation
If prior art machines are used for transferring solution between micrawell plates, then solution transfer can be performed, but the machines are expensive
Solution Approach 1:
The pin assemblies are designed to be autoclavable and replaceable rather than permanently maintained. This allows using simpler, cheaper materials and designs that can withstand sterilization, reducing manufacturing costs while maintaining automation capability
Solution Approach 2:
The pins automatically clean themselves by dipping into wash wells during their operational cycle, eliminating the need for separate cleaning mechanisms or manual intervention. This self-service feature reduces system complexity and manufacturing cost
3Adaptability or versatility
If manual handling of microwell plates is performed, then flexibility in transfer patterns can be achieved, but the handling burden on technicians increases
Solution Approach 1:
The system allows dynamic configuration of transfer patterns through programmable control of pin movements and dial rotations. Different transfer modes (complete plate copy, selective well transfer, interleaved patterns) can be programmed, providing flexibility while eliminating manual handling burden
Solution Approach 2:
The system incorporates programmable control that can be configured for different transfer patterns and volumes. The computer-controlled mechanism provides precise control over each pin's movement and timing, enabling flexible transfer patterns without requiring technician intervention during operation
Data Source
AI summary
An automated machine for transferring solution from a source microwell plate to a destination microwell plate. A plurality of pins is used for transferring the solution. The pins are attached to pin assemblies. The pin assemblies are attached to the circumference of a circular dial that is rotatably connected to the automated machine. The circular dial rotates the pins form a solution removal position to a solution transfer position and then to a pin cleaning position. Solution is removed from individual wells at the solution removal position and the solution is transferred to individual wells at the solution transfer position. The pins are cleaned at the pin cleaning position. A computer is programmed to control the automated machine and the transfer of solution. In a preferred embodiment, the computer is programmed to: 1) execute a saved transfer list, 2) accept a customized input list from an operator, 3) execute the customized input list, and 4) save the customized input list for later execution. In a preferred embodiment, the automated machine is utilized for transferring variable volumes of solution from the source microwell plate to the destination microwell plate.