Rotary Microfluidic Channel Switching for Simpler Flow Routing

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Solution Overview

Problem

Existing microfluidic devices require complex multi-valve structures for switching between and opening/closing multiple flow channels, leading to a complicated structure and high cost.

Innovation Solution

A microfluidic device with a flow channel switching assembly that allows for the rotation of liquid passing grooves to establish communication between multiple flow channels, simplifying the structure and enabling user-friendly operation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If conventional microfluidic devices use standard fabrication processes, then manufacturing simplicity is maintained, but manufacturing precision and device reliability are insufficient

Engineering Contradiction:
Improvedevice fabrication precisionVSAvoidfabrication process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The device is divided into multiple layers (first substrate, second substrate, intermediate layer) that can be fabricated separately using different processes and then assembled. This segmentation allows each layer to be optimized independently for precision while maintaining overall manufacturing simplicity through modular assembly.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The intermediate layer is positioned between and connects the first and second substrates, creating a nested multi-layer structure. This nesting approach enables complex three-dimensional microfluidic channels to be built from simpler two-dimensional layers, improving fabrication precision without requiring complex single-step processes.

Inventive Principle:
Principle #7Nested doll (Nesting)

2Reliability

If microfluidic devices use standard sealing methods, then device simplicity is maintained, but sealing reliability is insufficient for long-term stability

Engineering Contradiction:
Improvesealing reliabilityVSAvoidsealing structure complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

Sealing structures are pre-formed on the substrates before final assembly. The intermediate layer includes pre-configured sealing features that ensure reliable seals when layers are bonded together, preventing fluid leakage and maintaining long-term device stability without requiring complex post-assembly sealing procedures.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The device employs composite construction with different materials for different layers (e.g., PDMS, glass, or other compatible materials), allowing each material to be selected for its specific sealing properties. This composite approach enhances sealing reliability while keeping individual layer fabrication simple and well-established.

Inventive Principle:
Principle #40Composite materials

3Manufacturing precision

If microfluidic devices lack integrated control structures, then device simplicity is maintained, but fluid flow control precision is insufficient

Engineering Contradiction:
Improvefluid flow control precisionVSAvoiddevice structure complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

Control structures are integrated directly into the microfluidic device by merging them with the substrate layers during fabrication. This integration allows precise control of fluid flow through electric fields or other mechanisms while maintaining a compact, unified device structure rather than requiring separate external control systems.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The device incorporates pneumatic or hydraulic control mechanisms within the microfluidic channels themselves, using pressure differentials and fluid dynamics to achieve precise flow control. This approach enables high precision fluid manipulation without adding complex mechanical or electronic control structures.

Inventive Principle:
Principle #29Pneumatics and hydraulics

Data Source

PatentEP4640314A1Microfluidic device and microfluidic detection device
Publication Date: 2025.10.29 BGI HANGZHOU CYCLONESEQ TECHNOLOGY CO LTD
  • EP4640314A1 patent drawingFigure 1a~1b
  • EP4640314A1 patent drawingFigure 1c~1d
  • EP4640314A1 patent drawingFigure 2a~2b

AI summary

A microfluidic device (100) and a microfluidic detection apparatus (1000), wherein the microfluidic device (100) comprises a main body (110) and a flow channel switching assembly (120); the main body (110) is provided with multiple flow channels; the flow channel switching assembly (120) is rotatably connected to the main body (110); the flow channel switching assembly (120) is provided with liquid passing grooves; and the flow channel switching assembly (120) is configured to be rotatable relative to the main body (110) to adjust the position of the liquid passing groove, so that at least two of the multiple flow channels are in communication through the liquid passing groove. The microfluidic detection apparatus (1000) comprises a sensing device (200) and the microfluidic device (100).