Rotatable Implantable Drug Injection Guide Tube
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Solution Overview
Problem
Current drug injection methods for brain-related diseases face challenges in accuracy and safety due to difficulties in targeting specific brain areas, particularly in repeated administration, and the need for precise drug delivery while minimizing side effects and economic burden.
Innovation Solution
A drug injection device that includes a main body fixedly implanted between the skull and scalp, a movable part capable of directional adjustment, a sealing mechanism to prevent drug reversal and contamination, and a guide tube for precise drug delivery to the target point within the brain parenchyma, utilizing biocompatible materials for long-term implantation stability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a guide tube is changed in position or is inserted only in one direction, then the implantation procedure is simple, but it is difficult to re-inject a drug to an accurate position
Solution Approach 1:
The guide tube is designed with rotational capability around a central axis, transforming it from a static one-directional structure to a dynamic multi-directional structure. This allows the guide tube to be rotated to different angles (e.g., 0°, 45°, 90°, 135°) while maintaining its implanted position, enabling accurate drug delivery to multiple target points without requiring re-implantation.
Solution Approach 2:
The single implanted guide tube structure is designed to serve multiple functions: it can deliver drugs to the same lesion from different angles through rotation, and can potentially target multiple different lesions. This multi-functional design eliminates the need for multiple guide tubes or repeated implantation procedures.
2Duration of action of moving object
If the guide tube accuracy is lowered due to repeated administration to the same lesion, then the device can be used for repeated injections, but the drug injection device needs to be repeatedly implanted
Solution Approach 1:
The guide tube's rotational capability around the central axis provides a fresh angular approach for each injection session. Even when injecting the same lesion, the tube can be rotated to different angles, preventing accuracy degradation that would occur with repeated use in a fixed position, thereby eliminating the need for re-implantation.
Solution Approach 2:
The system changes the spatial parameter (angle/direction) of the guide tube while maintaining its implanted position. By varying the injection angle through rotation, the system refreshes the delivery path to the target, preventing accuracy loss associated with repeated injections through the same fixed trajectory.
3Object-affected harmful factors
If a sealing part is used to block the outside of the skull, then contamination is prevented, but the drug may reverse flow
Solution Approach 1:
The movable lid part acts as an intermediary component between the sealing part (which blocks external contamination) and the drug reservoir. This lid can selectively open to allow drug flow in the forward direction while the sealing part maintains the barrier against external contamination, preventing both contamination and reverse flow through coordinated operation of these two components.
Solution Approach 2:
The sealing system is divided into two functional segments: the sealing part that blocks external contamination and the movable lid part that controls drug flow direction. This segmentation allows each component to specialize in one function, with the lid managing forward flow while the seal manages external barrier, preventing both reverse flow and contamination.
Data Source
AI summary
Disclosed is a drug injection device that is fixedly implanted a patient's skull and scalp to inject a drug. The disclosed drug injection device includes a main body that is fixedly implanted in contact with a skull and has an internal hole; a main body fixing part that has an internal hole to be adjacent to the main body and is fixedly coupled to the main body; a movable part that is positioned between the main body and the main body fixing part, has a drug injection hole at a central part thereof, and is able to change its direction to a target point; a sealing part that is configured to seal the drug injection hole of the movable part, into which an injection needle for injecting a drug is inserted; a movable lid part that is positioned above the sealing part to close and fix the movable part, prevents the sealing part from being separated and escaping outside, and identifies an implantation position of the drug injection device to guide a point for repeated administration; and at least two fastening members that fasten an upper part of the main body and an upper part of the main body fixing part to the skull, in which the main body includes a support part that is positioned above the skull for support, an outer diameter of the support part is smaller than an outer diameter of the main body fixing part and is greater than an outer diameter of the movable part, and the main body and the main body fixing part are adjacently coupled to each other to accommodate and fix the movable part in the internal hole of the main body.


