Rotatable Roll Squeezing Flexible Drug Container

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Solution Overview

Problem

Existing drug delivery devices face challenges with dose accuracy due to friction between rigid cartridges and pistons, and they often require complex mechanisms for reliable operation.

Innovation Solution

A drug delivery device featuring a flexible container with a rotatable squeezing member that converts rotational motion into axial displacement, eliminating the need for a rigid cartridge and reducing friction, while maintaining high dose accuracy through a check valve and compensation member for reliable fluid communication.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a rigid cartridge with piston is used for dispensing drug, then the device structure is simple, but friction between piston and cartridge reduces dose accuracy

Engineering Contradiction:
Improvedose accuracyVSAvoiddevice structure
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts the piston from the traditional rigid cartridge system and replaces it with a flexible container that can be squeezed directly. This eliminates the piston-cartridge friction interface while maintaining the dispensing function through the flexible container's deformation under compression.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs a flexible container made of deformable material that can be compressed to dispense the drug. The flexible shell replaces the rigid cartridge-piston system, allowing volume reduction and drug expulsion through elastic deformation without sliding friction.

Inventive Principle:
Principle #30Flexible shells and thin films

2Measurement precision

If a rotatable squeezing member is used to squeeze the flexible container, then dose accuracy is improved, but the mechanism complexity increases

Engineering Contradiction:
Improvedose accuracyVSAvoidmechanism complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent uses a rotatable squeezing member that converts rotational motion into axial compression of the flexible container. This dynamic mechanism allows controlled, progressive squeezing through rotation, enabling precise dose delivery while maintaining operational reliability through a simple rotary interface.

Inventive Principle:
Principle #15Dynamics

3Reliability

If the flexible container and squeezing member are axially displaceable relative to each other, then friction is reduced, but operational reliability may be compromised

Engineering Contradiction:
Improveoperational reliabilityVSAvoidmechanism complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent introduces a second degree of freedom by allowing both axial displacement and rotation of the squeezing member. This multi-dimensional motion capability ensures reliable operation by decoupling the squeezing action from strict axial alignment requirements, accommodating manufacturing tolerances and assembly variations.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device achieves improved dose accuracy and reliability by minimizing friction and simplifying the mechanism, allowing for efficient and precise drug delivery without the need for a rigid cartridge, and facilitating easy replacement of flexible containers.

Implementation Method 1

the relative axial displacement between squeezing member and flexible container and the rotation of the squeezing member are frictionally coupled to one another

Methodology Applied
Scientific EffectFriction: Friction

Data Source

PatentEP2432524B1Drug delivery device and use of a rotatable roll in a drug delivery device
Publication Date: 2017.04.12 SANOFI AVENTIS DEUT GMBH
  • EP2432524B1 patent drawing
  • EP2432524B1 patent drawing
  • EP2432524B1 patent drawing

AI summary

A drug delivery device (1) is provided which comprises a housing (2), a dispensing end (3) for dispensing a drug (7) from the drug delivery device, a flexible container (6) for holding the drug, the flexible container comprising an outlet (8), the outlet being connected to the dispensing end, and a squeezing member (11) for squeezing the flexible container, wherein, for dispensing a dose of the drug from the drug delivery device, the squeezing member and the flexible container are axially displaceable relative to one another, the squeezing member rotating with respect to the housing during the relative axial displacement and squeezing the flexible container, thereby urging the dose of the drug from the container through the outlet. Furthermore, using a rotatable roll in a drug delivery device is described.