Rotating Compression Member for High Viscosity Medicament Delivery

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Solution Overview

Problem

Existing medical injector devices face challenges in reliably and completely delivering high viscosity and large volume medicaments over extended periods, which is crucial for effective treatment of medical conditions.

Innovation Solution

A medicament delivery system comprising a support member, a compression member, a collapsible medicament reservoir, and a mechanical coupling with a biasing element, where rotation of the compression member relative to the support member reduces the gap between them, collapsing the reservoir and expelling the medicament.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If a large volume medicament reservoir is used to deliver high viscosity medicaments, then the delivery capacity is improved, but the device complexity increases

Engineering Contradiction:
Improvemedicament volumeVSAvoiddevice complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The compression member transitions from a static structure to a dynamic rotating component that converts rotational motion into linear compression. This dynamic mechanism allows a relatively simple structure to achieve reliable compression of large volume, high viscosity medicaments through rotational actuation rather than complex linear actuation systems.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The mechanism converts rotational motion (circular dimension) into linear compression (straight line dimension) through the mechanical coupling between the compression member and support member. This dimensional transformation allows the use of simple rotational actuators to achieve the linear compression force needed for large volume medicament delivery.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Reliability

If the compression member is moved closer to the support member to collapse the reservoir, then the medicament delivery reliability is improved, but the mechanism complexity increases

Engineering Contradiction:
Improvemedicament delivery reliabilityVSAvoidmechanism complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The mechanical coupling merges the compression member and support member into an integrated rotational system. By combining these components with direct rotational coupling, the patent eliminates the need for separate linear actuation mechanisms, thereby improving reliability through simpler, more robust direct-contact compression while reducing overall mechanism complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The compression member is designed to self-compress the reservoir through its own rotational motion. As the compression member rotates, its geometry and the mechanical coupling automatically convert this rotation into the linear motion needed to collapse the reservoir, eliminating the need for additional control mechanisms and simplifying the overall system while ensuring reliable medicament delivery.

Inventive Principle:
Principle #25Self-service

3Force

If a mechanical coupling with multiple connecting members is used to convert rotation to linear motion, then the compression effectiveness is improved, but the device complexity increases

Engineering Contradiction:
Improvecompression forceVSAvoidmechanical coupling complexity
Core Design Contradiction:
ForceVSDevice complexity

Solution Approach 1:

The connecting members utilize spherical or curved joint geometries that naturally convert rotational motion into linear compression through geometric constraints. This curved geometry approach generates effective compression force through simple rotational input, eliminating the need for complex linkage mechanisms while maintaining high compression effectiveness for viscous medicament delivery.

Inventive Principle:
Principle #14Spheroidality (Curvature)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system ensures reliable and complete delivery of medicaments by efficiently collapsing the reservoir and expelling the medicament, addressing the challenges of high viscosity and large volume deliveries.

Implementation Method 1

a biasing element connected to the compression member and configured to exert a rotational force on the compression member relative to the support member

Methodology Applied
Scientific EffectElasticity: Elasticity

Data Source

PatentEP3484543B1Medicament delivery system
Publication Date: 2025.05.21 SANOFI SA(FR)
  • EP3484543B1 patent drawingFigure 1
  • EP3484543B1 patent drawingFigure 2
  • EP3484543B1 patent drawingFigure 3

AI summary

A medicament delivery system for use with medicament delivery device comprises a support member, a compression member spaced from the support member to define a gap therebetween, a mechanical coupling between the support member and the compression member comprising a plurality of connecting members extending between the support member and the compression member, and a biasing element connected to the compression member and configured to exert a rotational force on the compression member relative to the support member. The mechanical coupling is configured such that rotation of the compression member relative to the support member causes the compression member to be drawn towards the support member to reduce the gap therebetween.