Rotating Disk Magnetic Pattern for Miniaturized NMR ESR Analysis
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current NMR and ESR devices are too large for field or home use and require significant sample volumes, limiting their application in versatile, rapid, and efficient chemical analysis and medical diagnostics.
Innovation Solution
A miniaturized on-chip NMR or ESR device with a rotatable disk featuring magnetic patterns, a microcoil, and a servo-control mechanism, allowing for versatile and efficient analysis by generating static and excitation magnetic fields within a sample, enabling NMR or ESR detection on a small scale.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If conventional NMR and ESR devices are used, then analysis capability is provided, but device size becomes too large for field or home use
Solution Approach 1:
The patent divides the conventional NMR/ESR device into separate functional modules: a static magnetic field generator (permanent magnets), an oscillating magnetic field generator (rotating disk with magnetic patterns), and a detection unit (microcoil). This segmentation allows each component to be miniaturized independently, enabling portable operation while maintaining analysis capability.
Solution Approach 2:
The patent integrates multiple functional components within a compact housing structure. The rotating disk with magnetic patterns is positioned within the device body, the microcoil is embedded in the detection unit, and permanent magnets are incorporated into the magnetic field generation system. This nested arrangement minimizes overall device volume while preserving all necessary functions for NMR/ESR analysis.
2Adaptability or versatility
If conventional NMR devices are used, then analysis is performed, but large sample volumes are required which limits mixing and heating activities
Solution Approach 1:
The detection unit employs a microcoil that can be positioned to interact with very small sample volumes. The magnetic field generation system can be configured to concentrate magnetic field strength in specific regions, allowing analysis of micro-scale samples. This segmentation of the detection system enables versatile sample volume requirements from nanoliters to microliters.
Solution Approach 2:
The patent utilizes the relationship between magnetic field strength and sample volume by adjusting the current density in the microcoil and the strength of permanent magnets. This allows the same device to accommodate different sample volumes by changing operational parameters, providing flexibility for various analysis applications without requiring physical modification of the device.
3Volume of moving object
If miniaturized on-chip NMR/ESR device is implemented, then portability is achieved, but device complexity increases due to integration of multiple components
Solution Approach 1:
The patent combines the static and oscillating magnetic field generation capabilities into a single integrated device housing. The rotating disk mechanism is merged with the microcoil detection unit, and both permanent magnets and electromagnet components are integrated into a compact arrangement. This merging reduces the number of separate devices needed while maintaining all necessary functions.
Solution Approach 2:
The rotating disk with magnetic patterns serves multiple functions: it generates the oscillating magnetic field for NMR/ESR excitation, acts as a mechanical driver for the detection system, and can be configured with different magnetic patterns for different analysis modes. This multi-functionality reduces the overall component count and simplifies the integrated device design.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables portable, flexible, and efficient NMR or ESR analysis on-site, accommodating small sample volumes and integrating with microfluidic devices for various applications, including medical diagnostics and chemical analysis.
Implementation Method 1
the magnet is to generate a static magnetic field across the sample holding space
Implementation Method 2
the magnetic pattern on the rotating disk is to generate an excitation magnetic field across the sample holding space
Implementation Method 3
an NMR or ESR is generated within a sample contained in the space
Implementation Method 4
an NMR or ESR is generated within a sample contained in the space
Data Source
AI summary
An embodiment of the invention relates to a device for performing NMR or ESR analysis. The device comprises a detection unit, a magnet, and a disk having a magnetic pattern. The detection unit comprises a sample holding space for holding a sample and a microcoil for detecting NMR or ESR signals generated within the sample. The magnet generates a static magnetic field within the sample. The disk and magnetic pattern, when rotating, generate an excitation magnetic field, which, together with the static magnetic field, creates an NMR or ESR within the sample. Other embodiments of the invention encompass methods for performing NMR or ESR analysis using the device and methods of making such devices.