Rotating Drum Capping Device for Microplate Tube Handling

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Solution Overview

Problem

Existing microplate systems face challenges in efficiently capping and decapping multiple tubes, particularly in standardized microplates with 96, 384, or 1536 wells, due to the small size of the tubes and the difficulty in automated handling.

Innovation Solution

A capping and decapping device comprising a drum member with a cap stamp and a frame structure, which allows for rotational movement of the drum member to efficiently cap and decap tubes by moving the microplate along predefined paths.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If standard handling robots are used for capping and decapping tubes in microplates, then the tubes can be processed, but the operation becomes cumbersome and inefficient

Engineering Contradiction:
Improvecapping and decapping operationVSAvoidprocessing efficiency
Core Design Contradiction:
Ease of operationVSProductivity

Solution Approach 1:

The device segments the capping and decapping operations into distinct functional zones within a single integrated unit. The drum member is divided into multiple sectors, each equipped with capping tools configured for specific tube types and positions in the microplate, allowing specialized handling for different tube configurations

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The capping and decapping device is designed as a multi-functional unit that can handle multiple tube types (e.g., 0.2 mL, 0.5 mL, 1.5 mL microcentrifuge tubes) and perform both capping and decapping operations within a single device, eliminating the need for separate standard handling robots for different operations

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Productivity

If manual capping and decapping methods are used, then the process can be completed, but the handling efficiency is reduced and automation cannot be achieved

Engineering Contradiction:
Improvehandling efficiencyVSAvoidautomated handling
Core Design Contradiction:
ProductivityVSExtent of automation

Solution Approach 1:

The device incorporates self-positioning mechanisms where the drum member automatically orients itself relative to the microplate based on the position of guide pins in guide holes. This self-alignment feature enables automated operation without requiring complex external positioning systems or manual intervention for each tube

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The drum member acts as an intermediary component that bridges the microplate and the capping/decapping tools. It carries multiple capping tools in its sectors and positions them precisely over the tubes through rotational movement, enabling automated transfer of caps without direct manual handling

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If a drum member with multiple sectors is used, then multiple tube types can be handled, but the device complexity increases

Engineering Contradiction:
Improvetube type compatibilityVSAvoiddrum member structure
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The drum member is designed with asymmetric sectors of different sizes and configurations, each tailored to specific tube types and positions. This asymmetric design allows the single drum member to accommodate multiple tube formats (e.g., different well depths, tube diameters) without requiring multiple identical drums, simplifying the overall system while maintaining versatility

Inventive Principle:
Principle #4Asymmetry

Data Source

PatentUS20250177987A1Capping and decapping device, capping and decapping system and method of capping and decapping a tube
Publication Date: 2025.06.05 F HOFFMANN LA ROCHE INC
  • US20250177987A1 patent drawing
  • US20250177987A1 patent drawing
  • US20250177987A1 patent drawing

AI summary

A capping and decapping device for reversibly removing and mounting a cap to and from a tube received in a tube seat of a microplate includes a drum member having a cap stamp, and a frame supporting the drum member such that the drum member is rotatable relative to the frame. The device is configured to rotate the drum member in a first rotational direction when the microplate is moved relative to the frame in a first path direction, and to rotate the drum member in a second rotational direction when the microplate is moved relative to the frame in a second path direction. The cap stamp is configured to remove the cap from the tube when the microplate is moved in the first path direction and is configured to connect the cap to the tube when the microplate is moved in the second path direction.