Rotating Oral Drug Delivery Attachment With Breakable Cover
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing oral drug delivery systems face challenges in delivering low permeable and low water soluble active drug substances due to stability issues and limited absorption from the gastrointestinal tract, leading to ineffective oral administration.
Innovation Solution
An oral drug delivery device with a rotating attachment part configured to penetrate gastrointestinal tissue, featuring a cover that breaks or weakens during rotation, allowing efficient drug delivery and attachment to mucous membranes.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If multiple attachment parts are used to improve attachment ability, then the attachment reliability improves, but the device complexity increases and the number of parts that could break increases
Solution Approach 1:
The patent merges multiple attachment parts into a single integrated attachment structure. The attachment part is designed as one piece that can engage with gastrointestinal tissue, eliminating the need for multiple separate components while maintaining attachment reliability. This reduces the number of parts that could potentially break or fail during use.
2Productivity
If the attachment part is rotated at higher angles to improve insertion efficiency, then the insertion speed improves, but the force required for rotation increases
Solution Approach 1:
The patent employs a dynamic rotation mechanism where the attachment part can rotate about a rotation axis that is not fixed relative to the longitudinal axis. This allows the attachment part to rotate at higher angles (larger than 45 degrees with the longitudinal axis) to improve insertion efficiency into gastrointestinal tissue while the mechanism itself adapts to the force requirements through its engineered rotation capability.
3Reliability
If the cover is made stronger to protect internal components, then the protection reliability improves, but the time required to break or weaken the cover increases
Solution Approach 1:
The patent incorporates a cover weakening feature that is designed to break or weaken the cover at a predetermined location during the insertion process. This preliminary action is built into the device structure, allowing the cover to be intentionally designed to fail at a specific point to release the attachment part for tissue engagement, rather than requiring prolonged force to break a uniformly strong cover.
Data Source
AI summary
An oral drug delivery device and a pharmaceutical composition is disclosed, the oral drug delivery having a longitudinal axis and extending from a first end to a second end, the oral drug delivery device comprising a cover; a body; a first attachment part having a first distal end and configured to deliver an active drug substance; and an actuator mechanism engaged with the first attachment part and configured to rotate the first attachment part about a first rotation axis forming an angle larger than 45 degrees with the longitudinal axis, the oral drug delivery device configured to break or weaken the cover prior to or during rotation of the first attachment part.