Rotating Tissue Sample Holder Fluid Management
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Solution Overview
Problem
Existing biopsy devices face challenges in efficiently managing fluid distribution during tissue sample collection, which can lead to unnecessary compression or trauma to the tissue samples, especially in multi-chamber tissue sample holders where vacuum control is crucial for proper sample handling.
Innovation Solution
The biopsy device incorporates a tissue sample holder with a rotatable member and fluid management tube, allowing for discrete sample collection modes and controlled vacuum distribution through a fluid circuit, ensuring even vacuum application to individual chambers and minimizing sample trauma.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If vacuum is applied to multi-chamber tissue sample holder, then tissue samples can be collected and held, but fluid distribution control becomes complex and may cause sample compression or trauma
Solution Approach 1:
The tissue sample holder is divided into multiple independent chambers, each capable of being individually isolated or connected to the vacuum source. This segmentation allows selective vacuum application to specific chambers rather than applying vacuum uniformly to all chambers, thereby simplifying fluid distribution control while maintaining reliable sample handling in each chamber.
Solution Approach 2:
The system employs dynamic control of fluid distribution through movable partitions or adjustable connections between chambers and the vacuum source. This allows the vacuum system to adaptively connect or isolate specific chambers based on procedural needs, enabling complex sample handling requirements to be met without permanently complexifying the fluid distribution infrastructure.
2Adaptability or versatility
If multiple chambers are used for sample collection, then both bulk and individual tissue collection modes are enabled, but vacuum control precision becomes more difficult to maintain
Solution Approach 1:
Each chamber is designed as a discrete unit with independent vacuum control capability through separate fluid distribution channels or selectively controllable connections. This segmentation enables the system to maintain precise vacuum control in each chamber independently, even when multiple chambers are present and when switching between bulk and individual collection modes.
Solution Approach 2:
The system introduces intermediary control elements such as valves, flow regulators, or controllable partitions that mediate between the vacuum source and individual chambers. These intermediaries enable precise vacuum control to be maintained across multiple chambers by allowing independent adjustment of vacuum parameters for each chamber or for specific groups of chambers during mode transitions.
3Reliability
If vacuum is applied to hold tissue samples, then samples are secured for transport and analysis, but excessive vacuum may compress or traumatize the tissue
Solution Approach 1:
The vacuum force is distributed non-uniformly across different chambers or regions based on local requirements. Individual chambers can be assigned different vacuum levels appropriate to their specific contents and transport needs, allowing samples to be securely held without subjecting them to excessive or unnecessary vacuum forces that would cause compression or trauma.
Solution Approach 2:
The vacuum level applied to each chamber can be dynamically adjusted during the procedure based on real-time requirements. The system can transition from higher vacuum levels during sample collection to lower vacuum levels during transport or analysis phases, thereby maintaining sample stability while minimizing tissue compression and trauma at different procedural stages.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This design enhances flexibility in biopsy procedures by allowing both bulk and individual tissue collection, providing improved sample handling and analysis capabilities while reducing sample trauma through precise fluid management.
Implementation Method 1
provides vacuum through the body assembly to the tissue sample holder assembly
Data Source
AI summary
A biopsy device includes a body, an axial tube, a needle assembly, and a tissue sample holder. The body includes a proximal end. The axial tube extends proximally from the proximal end of the body. The axial tube includes at least one aperture. The needle assembly extends distally from the body and includes a needle and a cutter. The cutter is movable relative to the needle. The tissue sample holder is configured to removably couple to a proximal end of the body such that the axial tube is disposed within the tissue sample holder. At least a portion of the tissue sample holder is rotatable relative to the body such that the tissue sample holder is configured to rotate about the axial tube. The tissue sample holder is in fluid communication with the axial tube through the at least one aperture.


