Rotational Source Localization in Heart Rhythm Disorders
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Solution Overview
Problem
Current methods fail to accurately define the rotational source and its propagation associated with complex heart rhythm disorders, such as atrial fibrillation, ventricular tachycardia, and ventricular fibrillation, making targeted treatment challenging.
Innovation Solution
A system and method that calculates the center locations of wave fronts, determines a rotational path, and generates a clinical representation to identify the region of heart tissue associated with the rotational path, allowing for the determination of a likely core of the rotational source, which can be treated to eliminate the rhythm disorder.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If traditional methods are used to identify heart rhythm disorder sources, then treatment can be attempted, but the location of the rotational source cannot be accurately identified, leading to ineffective treatment
Solution Approach 1:
The patent segments the complex rotational source into discrete measurable components: wave front center locations at multiple time points, rotational paths, and likely cores. By breaking down the rotational source into these segmentable elements, the system can calculate and identify each component separately, achieving precise localization that was previously impossible with traditional unified approaches.
2Loss of information
If a rotational source is identified with diffuse activation wave fronts, then the source location can be marked, but the exact core and propagation path remain undefined, making targeted treatment difficult
Solution Approach 1:
The patent implements a feedback mechanism where activation information from multiple electrodes is continuously collected and processed to calculate wave front center locations at successive time points. This feedback loop allows the system to track the rotational path dynamically and refine the identification of the likely core, converting diffuse information into precise spatial and temporal data that guides targeted treatment.
3Loss of time
If immediate treatment is provided upon identifying the rotational source, then treatment time is reduced, but without a defined rotational path and core, the treatment may not be precise enough to spare healthy tissue
Solution Approach 1:
The patent performs preliminary calculations of wave front center locations, rotational paths, and likely cores immediately upon collecting sufficient activation data. This preliminary action establishes the precise treatment target before actual treatment begins, allowing immediate targeted intervention with full spatial definition of the rotational source, thereby achieving both speed and precision simultaneously.
Data Source
AI summary
An example system and method of defining a rotational source associated with a heart rhythm disorder are disclosed. A plurality of center locations of wave fronts are calculated at a plurality of time points associated with the heart rhythm disorder. A rotational path that connects the plurality of center locations is then determined. Thereafter, a clinical representation that identifies a region of heart tissue associated with the rotational path is generated. The system and method can also determine a likely core associated with the rotational path. A plurality of relative diffusion shapes associated with the plurality of the center locations is calculated. A plurality of intersecting points of a smallest relative diffusion shape and other relative diffusion shapes is determined within the rotational path. A bounded polygon of the intersecting points is defined as the likely core.