Rotationally biased insertion mechanism for drug delivery pump

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Solution Overview

Problem

Existing drug delivery systems, such as manually operated syringes and injection pens, lack precision, reliability, and convenience for the parenteral delivery of liquid medicines, and available ambulatory infusion pumps are expensive, difficult to program, and bulky.

Innovation Solution

The development of drug delivery pumps with integrated safety mechanisms, including insertion mechanisms that provide sterile fluid pathways only upon proper activation, and automatic safety features to prevent excessive or rapid drug delivery.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manually operated syringes and injection pens are used for drug delivery, then the device is simple and easy to operate, but precision and reliability of drug delivery are insufficient

Engineering Contradiction:

Improveease of operationVSAvoidprecision of drug delivery

Core Design Contradiction:

Ease of operationVSMeasurement precision

Solution Approach 1:

The patent replaces manual mechanical operation with an automated pump system that uses a motor-driven plunger to deliver precise volumes of medication. The pump mechanism provides controlled, programmable delivery while maintaining patient-friendly operation through electronic controls and sensors.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If ambulatory infusion pumps are used for drug delivery, then precision and reliability of drug delivery are improved, but the device becomes expensive, bulky, and difficult to program

Engineering Contradiction:

Improveprecision of drug deliveryVSAvoidcomplexity of device

Core Design Contradiction:

Measurement precisionVSDevice complexity

Solution Approach 1:

The patent divides the infusion pump into modular components: a compact pump body, a removable medication reservoir, and an integrated control system. This segmentation allows the device to be smaller and simpler while maintaining precision delivery capabilities through the coordinated function of each module.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The pump incorporates automatic safety features including sensors that detect improper installation, automatic priming capabilities, and built-in dosage calculation functions. These self-service features eliminate the need for complex programming and reduce operational complexity while maintaining precision.

Inventive Principle:

Principle #25Self-service

3Device complexity

If traditional drug delivery systems are used, then the device is simple in structure, but safety features to prevent overdose or rapid administration are lacking

Engineering Contradiction:

Improvesimplicity of device structureVSAvoidsafety of drug delivery

Core Design Contradiction:

Device complexityVSReliability

Solution Approach 1:

The pump performs preliminary safety checks before drug delivery, including verification of reservoir installation, priming of the delivery system, and confirmation of proper needle/cannula placement. These preliminary actions prevent unsafe operation while keeping the overall device design simple.

Inventive Principle:

Principle #10Preliminary action

Solution Approach 2:

The system incorporates sensors that provide real-time feedback on delivery status, reservoir level, and system integrity. This feedback mechanism enables automatic safety responses such as pausing delivery or alerting the user without adding significant structural complexity to the device.

Inventive Principle:

Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The proposed solution offers a precise, reliable, and cost-effective alternative for drug delivery, ensuring patient safety by preventing accidental overdose or rapid drug administration, while being compact and user-friendly.

Implementation Method 1

one or more rotational biasing members initially held in an energized state with at least a portion of the rotational biasing member engaged with the housing; Rotation of the housing caused by de-energizing of the rotational biasing member

Methodology Applied

Scientific EffectRotational biasing member: Spring

Implementation Method 2

a retraction biasing member; The retraction biasing member is held initially in an energized state between the hub and the sleeve

Methodology Applied

Scientific EffectRetraction biasing member: Spring

Data Source

PatentUS12208237B2Rotationally biased insertion mechanism for a drug delivery pump

Publication Date: 2025.01.28 AMGEN INC

AI summary

An insertion mechanism for a drug pump includes an insertion mechanism housing; a sleeve; a rotational biasing member initially held in an energized state; a retraction biasing member and a hub connected to a proximal end of a needle, wherein the retraction biasing member is held initially in an energized state between the hub and the sleeve. The needle is inserted into a target tissue by the rotational biasing member and interaction between the hub and housing. Retraction of the needle is caused by decompressing or de-energizing of the retraction biasing member. A drug delivery pump includes an activation mechanism, a drive mechanism, a sterile access connection, and the insertion mechanism. Assembly and operation methods are provided.