Composite Gel for Rumen-Protected Lipid Delivery

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Solution Overview

Problem

Existing methods for reducing saturated fats in ruminant food products, such as those from cattle, are ineffective due to toxic effects on rumen microorganisms and limited protection against biohydrogenation, leading to decreased animal productivity and unsatisfactory fatty acid composition in meat and dairy products.

Innovation Solution

A composite gel is created by emulsifying a lipid filler composition into an aqueous protein matrix solution, forming a dispersed phase of lipid droplets within a cross-linked protein matrix, which protects nutrients and supplements from degradation and biohydrogenation in the rumen, allowing for the delivery of polyunsaturated fats and other supplements to the lower digestive tract.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If large amounts of polyunsaturated fats are included in ruminant feed to reduce saturated fats in meat and dairy products, then the fatty acid composition of meat and dairy products is improved, but rumen microorganisms are toxically affected and animal productivity decreases

Engineering Contradiction:
Improvefatty acid compositionVSAvoidanimal productivity
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The feed is segmented into two functional components: a rumen-protected composite gel containing polyunsaturated fats that passes through the rumen unchanged, and a separate rumen-available protein source. This segmentation allows the polyunsaturated fats to reach the lower digestive tract without toxicifying rumen microbes, while animals receive adequate energy from rumen-digested proteins, thereby resolving the contradiction between improving fatty acid composition and maintaining productivity

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The composite gel acts as an intermediary carrier that protects polyunsaturated fats from rumen biohydrogenation. The gel matrix shields the fats from rumen microbes during passage, allowing them to be released intact in the lower digestive tract. This intermediary mechanism enables the fats to fulfill their function of modifying meat and dairy fatty acid composition without directly contacting and toxicifying rumen microorganisms

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If polyunsaturated fats are added below toxic levels to protect rumen microbes, then animal productivity is maintained, but the saturation of fats in meat and milk is not reduced due to biohydrogenation

Engineering Contradiction:
Improveanimal productivityVSAvoidfatty acid composition
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The polyunsaturated fats are pre-encapsulated in a composite gel structure before feeding. This preliminary encapsulation prevents rumen biohydrogenation from occurring, ensuring that the fats remain unsaturated when they reach the lower digestive tract. The gel is designed to be digested after the rumen passage, at which point the protected fats are released in their original unsaturated form, thus achieving both productivity maintenance and fatty acid composition improvement

Inventive Principle:
Principle #10Preliminary action

3Reliability

If calcium salts of fatty acids are used to reduce biohydrogenation, then protection against modification is improved, but the calcium salts are unappetizing and undergo dissociation in the rumen

Engineering Contradiction:
Improveprotection against biohydrogenationVSAvoidappetizability
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The invention changes the physical and chemical parameters of the fat delivery system by using a composite gel matrix with specific pH-responsive properties. The gel maintains structural integrity at rumen pH levels, preventing calcium salt dissociation and biohydrogenation, but becomes digestible at lower pH in the lower digestive tract. This parameter change approach eliminates the unappetizing taste issue while maintaining reliable protection against modification

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composite gel effectively reduces saturated fats and increases unsaturated fats in milk and meat, enhancing animal productivity and nutritional quality while being non-toxic to rumen microbes and palatable to animals.

Implementation Method 1

Composite gels of the invention can be, e.g., fed to cattle or other ruminants, whereby lipids, nutrients, and/or bioactive molecules can pass through the rumen without degradation, modification, or removal

Methodology Applied
Scientific EffectPhysical containment: Physical Containment

Implementation Method 2

A composite gel is created by emulsifying a lipid filler composition into an aqueous protein matrix solution, forming a dispersed phase of lipid droplets within a cross-linked protein matrix

Methodology Applied
Scientific EffectEmulsion: Emulsion

Implementation Method 3

In biohydrogenation, the majority of the unsaturated fatty acids (e.g. fatty acids containing double bonds between some carbons) are hydrogenated to saturated fatty acids (e.g. fatty acids containing no double bonds between some carbons)

Methodology Applied
Scientific EffectBiohydrogenation: Hydrogenation

Data Source

PatentUS7700127B2Method and compositions for preparing and delivering rumen protected lipids, other nutrients and medicaments
Publication Date: 2010.04.20 RGT UNIV OF CALIFORNIA
  • US7700127B2 patent drawing
  • US7700127B2 patent drawing
  • US7700127B2 patent drawing

AI summary

This invention provides composite gels to, e.g., efficiently deliver unmodified amino acids, lipids, and/or feed supplements through the rumen of a ruminant animal. The invention also provides methods to make and use composite gels.