Ryanodine Insecticide and Baculovirus Composition for Rapid Pest Control
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Solution Overview
Problem
Current pesticides face challenges such as rapid pest resistance, high development costs, and environmental toxicity, with limited new active ingredients being introduced due to the slow pace of innovation and the need for more selective and safer alternatives.
Innovation Solution
A pesticide composition combining a ryanodine receptor insecticide or diamide insecticide with baculovirus, diluted 100-3000 times for application, targeting third or older instars, with concentrations of 0.01-75% insecticide and 10^7-10^12 PIB/ml virus, to enhance efficacy and reduce resistance.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If chemical pesticides are used to control pests, then pest control effectiveness is achieved, but pest resistance develops rapidly and environmental toxicity increases
Solution Approach 1:
The patent combines a ryanodine receptor insecticide or diamide insecticide with baculovirus in a single pesticide composition. This combination achieves synergistic effects that enhance pest control effectiveness while reducing the development of pest resistance and minimizing environmental toxicity compared to using chemical pesticides alone.
Solution Approach 2:
The invention creates a composite pesticide composition integrating two different types of agents: a chemical insecticide (ryanodine receptor or diamide) and a biological agent (baculovirus). This composite approach leverages the advantages of both chemical and biological pesticides to achieve superior control with reduced harmful effects.
2Reliability
If new chemical pesticides are developed to maintain effectiveness, then pest control reliability is improved, but development cost and time increase significantly
Solution Approach 1:
By combining existing ryanodine receptor or diamide insecticides with baculovirus, the patent avoids the need to develop entirely new chemical pesticides from scratch. This combination approach maintains pest control effectiveness while reducing development costs and time compared to creating new chemical compounds.
3Loss of time
If pesticides are applied at high concentrations to ensure rapid kill, then pesticidal time is reduced, but human and environmental exposure to chemicals increases
Solution Approach 1:
The composite composition of insecticide and baculovirus enables rapid pest kill (50% death in two days, 90% death in three to four days) while reducing the need for high chemical concentrations. The biological agent contributes to the rapid kill effect, thereby reducing human and environmental exposure to chemicals.
Solution Approach 2:
The baculovirus acts as an intermediary that enhances the pesticidal effect without requiring high concentrations of chemical insecticides. The virus-mediated killing mechanism reduces chemical exposure while maintaining rapid pest control.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This combination significantly shortens the pesticidal time, achieving 50% death in two days and 90% death in three to four days, while maintaining long-term effectiveness and reducing human and environmental exposure to chemicals, with synergistic effects up to four folds compared to using the insecticide alone.
Implementation Method 1
a ryanodine receptor insecticide or a diamides insecticide
Implementation Method 2
Ryanodine receptor modulators are a new kind of synthetic pesticide, which are effective to Lepidoptera pests including the European corn borer, sugar cane borer, codling moth, apple borer and gypsy moth
Implementation Method 3
baculovirus
Implementation Method 4
The baculoviruses are a family of large rod-shaped viruses that can be divided into two genera: nucleopolyhedroviruses (NPV) and granuloviruses (GV)
Implementation Method 5
diluting the pesticide composition 100-3000 times
Data Source
AI summary
The present invention provides a method of shortening pesticidal time of the baculovirus to pest, comprising: (1) preparing a pesticide composition; (2) diluting the pesticide composition 100-3000 times; and (3) spraying the diluted pesticide composition on third or older instars in fields; wherein the pesticide composition comprises: (a) a ryanodine receptor insecticide or a diamides insecticide and (b) baculovirus, wherein the concentration of the ryanodine receptor insecticide or the diamides insecticide is 0.01-75% and the concentration of the nucleopolyhedrovirus is 107-1012 PIB/ml. The pesticide composition of the present invention can effectively reduce the lethal time to the pest compared to the baculovirus alone, and also can increase the control effect of the pest compared to the same concentration of the insecticide, when applied in field.