Saflufenacil Soluble Liquid Composition for Precipitation Stability

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Solution Overview

Problem

Saflufenacil is difficult to formulate into stable liquid formulations due to its low solubility in water and many organic solvents, leading to precipitation and poor stability, which complicates its use as an herbicide.

Innovation Solution

A soluble liquid composition comprising saflufenacil and an organic base, forming a complex that stabilizes saflufenacil in water, enhancing solubility and preventing sedimentation, allowing for high load formulations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If saflufenacil is formulated in water or organic solvents, then it can be applied as a liquid herbicide, but it precipitates and shows poor stability due to low solubility

Engineering Contradiction:
Improveliquid formulation applicabilityVSAvoidformulation stability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent uses an amine salt as an intermediary substance to bridge saflufenacil and water. The amine salt forms a soluble complex with saflufenacil that maintains stability in aqueous media, preventing precipitation while enabling liquid formulation application.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the chemical state of saflufenacil by converting it to an amine salt form. This parameter change in molecular structure and charge state dramatically improves water solubility and formulation stability while maintaining herbicidal activity.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If high concentrations of saflufenacil are used to reduce application frequency, then herbicidal effectiveness improves, but solubility and stability deteriorate

Engineering Contradiction:
Improveherbicidal effectivenessVSAvoidsolubility and stability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The amine salt conversion enables high concentrations of saflufenacil to be formulated in water without precipitation. The changed chemical parameters of the amine salt form allow sustained high-level effectiveness while maintaining solubility and stability.

Inventive Principle:
Principle #35Parameter changes

3Ease of manufacture

If conventional formulation methods are used, then manufacturing simplicity is maintained, but formulation complexity increases due to precipitation issues

Engineering Contradiction:
Improveformulation simplicityVSAvoidformulation complexity
Core Design Contradiction:
Ease of manufactureVSDevice complexity

Solution Approach 1:

Converting saflufenacil to an amine salt simplifies the formulation process by eliminating precipitation issues. The parameter change in chemical state allows straightforward aqueous formulation without complex stabilization additives or special manufacturing procedures.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition provides a stable, high-load saflufenacil solution that maintains solubility and stability, enabling effective herbicidal action with reduced amounts of active ingredient.

Implementation Method 1

A soluble liquid composition comprising saflufenacil and an organic base, forming a complex that stabilizes saflufenacil in water

Methodology Applied
Scientific EffectComplex formation: Chemical Bonding

Implementation Method 2

enhancing solubility and preventing sedimentation

Methodology Applied
Scientific EffectStabilization:

Data Source

PatentUS12543735B2Soluble liquid compositions of saflufenacil, method of preparation and use thereof
Publication Date: 2026.02.10 ADAMA AGAN LTD
  • US12543735B2 patent drawing
  • US12543735B2 patent drawing
  • US12543735B2 patent drawing

AI summary

The present invention relates to a soluble liquid (SL) composition comprising saflufenacil and an organic base. Optionally, the composition further comprises at least one agriculturally acceptable carrier and/or additives. The present invention further relates to a use of an amine salt of saflufenacil for preparing a soluble liquid composition.