Cellular Aging Composition Using SAMe and Adaptogenic Extracts
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Solution Overview
Problem
Current solutions fail to effectively address the signs of aging and its associated health issues, such as neurodegenerative diseases, cognitive decline, osteoporosis, and joint disorders, as life expectancy increases and more people are affected by these conditions.
Innovation Solution
A composition comprising S-Adenosyl-methionine, an adaptogenic plant extract, and a vitamin, specifically from groups like Astragalus, Dioscorea, and B vitamins, which work synergistically to combat stress and slow cellular aging by promoting DNA health, immune function, and reducing oxidative stress.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional single-compound supplements are used to address aging, then specific functions may be targeted, but overall effectiveness against multiple aging signs is insufficient
Solution Approach 1:
The patent combines three distinct compounds (SAMe, adaptogenic plant extract, and vitamin) into a single composition, where each component addresses different aspects of aging. SAMe supports DNA methylation and cognitive function, adaptogenic extract addresses oxidative stress and immune function, and vitamin provides additional antioxidant protection. This merging creates a comprehensive solution that simultaneously targets multiple aging-related functions with enhanced overall effectiveness.
Solution Approach 2:
The invention creates a composite supplement formulation integrating three chemically and functionally distinct compounds. This composite approach allows the composition to leverage the synergistic effects of each component - the methyl donor properties of SAMe, the adaptogenic and antioxidant properties of the plant extract, and the vitamin's protective functions - thereby achieving superior reliability against diverse aging signs compared to single-compound supplements.
2Adaptability or versatility
If multiple compounds are combined to address multiple aging functions, then versatility improves, but complexity of the composition increases
Solution Approach 1:
The composition is segmented into three distinct functional components, each addressing specific aging mechanisms. This segmentation allows for clear identification of each compound's role (SAMe for methylation, adaptogenic extract for oxidative stress, vitamin for antioxidant support) while maintaining overall simplicity in formulation and usage. The segmented structure makes the complex multi-function composition easier to understand, manufacture, and regulate.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively slows down cellular aging, reduces stress, and addresses various age-related health issues by enhancing DNA protection, immune function, and reducing inflammation and oxidative stress, thereby promoting overall bodily function and health.
Implementation Method 1
S-Adenosyl-methionine (SAM) is a metabolite involved as a coenzyme in the activity of DNA methyltransferases or histone methyltransferases. Supplementation with SAM makes it possible to avoid hypomethylation or hypermethylation of DNA
Implementation Method 2
SAM is involved in the synthesis of epinephrine (adrenaline) by nucleophilic substitution reaction with norepinephrine
Implementation Method 3
These plants reactivate resting immune cells, stimulating macrophages and promoting the regeneration of T and NK lymphocytes; inhibit lipid peroxidation particularly in the myocardium; and stimulate telomerase thus lengthening the shortest telomeres and protecting DNA from cellular aging
Implementation Method 4
Vitamin C is a powerful antioxidant which makes it possible to limit oxidative stress
Data Source
AI summary
The invention relates to a composition for slowing cellular ageing which comprises at least: S-Adenosyl-methionine; an extract of at least one adaptogenic plant selected among plants belonging to the Astragalus, Dioscorea, Schisandra, Panax, Eleuterococcus, Rosmarinus, Pfaffia, Morinda, Cordyceps or Lepidium genera; a vitamin selected among the B vitamins, vitamin C, or a mixture thereof; except for compositions comprising 7-keto-DHEA and an extract of one or more adaptogenic plants belonging to the Dioscorea or Lepidium genera. A liquid or solid food supplement can be characterised in that it comprises the composition. A dermatologically acceptable composition can be characterised in that it comprises at least 10 wt % of the composition.