Sample Analyzer Paired PRP PPP Sample Identification
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Solution Overview
Problem
Existing sample analysis methods for platelet aggregation require separate handling and confirmation of platelet rich plasma (PRP) and platelet poor plasma (PPP) samples to ensure they are from the same patient, which can lead to sample mix-ups if not properly confirmed.
Innovation Solution
A sample analyzer with a transporting part, measuring part, and controller that identifies and processes paired samples preprocessed differently, ensuring accurate analysis by measuring and generating results for both PRP and PPP samples obtained from the same subject.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If separate handling and confirmation of PRP and PPP samples is performed to ensure they are from the same patient, then measurement reliability is improved, but operation complexity and time consumption increase
Solution Approach 1:
The patent combines multiple sample handling operations into a single integrated process. The sample rack holds both PRP and PPP samples together, and the transporting part moves them simultaneously through the measuring part, which performs both measurements in one sequence, eliminating separate handling steps while maintaining identification accuracy through the controller's coordinated management
Solution Approach 2:
The patent uses identification information (such as barcodes or labels) copied from the original whole blood sample to tag both PRP and PPP samples. This copying of identification data ensures that the paired relationship between samples is maintained throughout the process without requiring manual confirmation, reducing operational complexity while preserving reliability
2Reliability
If separate handling and confirmation of PRP and PPP samples is performed, then sample mix-up prevention is improved, but analysis time increases
Solution Approach 1:
The patent performs preliminary pairing of PRP and PPP samples in the sample rack before measurement begins. The controller pre-configures the measurement sequence to process paired samples together, so that identification and pairing verification are completed in advance rather than during the measurement process, preventing mix-ups while minimizing time loss
Solution Approach 2:
The transporting part continuously moves the sample rack through the measuring part without interruption, and the measuring part performs measurements on PRP and PPP samples in a continuous sequence. This eliminates idle time between measurements while maintaining sample identification integrity through the controller's coordinated management throughout the continuous process
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system ensures accurate analysis of platelet aggregation by correctly identifying and processing paired PRP and PPP samples, reducing the risk of sample mix-ups and ensuring measurements are derived from the same subject.
Implementation Method 1
the respective light absorption of the PRP sample and the PPP sample is measured
Data Source
AI summary
Disclosed is a sample analyzer including a transporting part configured to transport a sample rack holding one or more samples, a measuring part configured to perform a measurement on the sample of the transported sample rack and a controller. The controller is programmed to perform an analysis of a predetermined item that requires at least first and second measurement results derived respectively from first and second samples obtained from the same subject and preprocessed in different ways, and if a measurement of the predetermined item is requested and a set of first and second samples obtained from the same subject and preprocessed in different ways are transported to the measuring part, the controller controls the measuring part to perform measurements on both of the first and second samples to derive the first and second measurement results and processes them to generate an analysis result of the predetermined item.