Sample Cartridge Carrier Base for Cooled FIB Transfer

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Solution Overview

Problem

Existing FIB processing systems face challenges in maintaining the cooled condition of samples, particularly living organisms, during processing and observation, and in safely transferring sample cartridges between stages without causing condition changes or breakage.

Innovation Solution

A sample cartridge carrier apparatus with a sub stage, carrier base, and carrier mechanism that includes a cooler block and retainer mechanism to maintain the cooled condition and facilitate safe transfer of sample cartridges between stages.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Temperature

If a tank containing liquid nitrogen is used to maintain the cooled condition of the sample, then the sample can be kept in a cooled condition, but the sample may change its condition or drop or break during tasks performed in the tank

Engineering Contradiction:
Improvecooled condition of sampleVSAvoidsample stability during transfer
Core Design Contradiction:
TemperatureVSReliability

Solution Approach 1:

A carrier base with a cooler block serves as an intermediary device between the liquid nitrogen tank and the sample cartridge. The carrier base receives the sample cartridge from the tank, maintains its cooled condition through the cooler block, and transports it to the sub stage, preventing direct handling and potential damage to the sample

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system is divided into separate functional components: the liquid nitrogen tank for cooling, the carrier base with cooler block for stable holding and transport, and the sample cartridge for sample containment. This segmentation allows each component to perform its specific function optimally without compromising sample integrity

Inventive Principle:
Principle #1Segmentation

2Reliability

If precise operations are performed to transfer the sample cartridge safely, then the sample condition can be maintained, but the user burden increases

Engineering Contradiction:
Improvesample condition maintenanceVSAvoiduser burden during transfer
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The retainer mechanism automatically engages with the sample cartridge when the carrier base is positioned correctly, eliminating the need for precise manual operations. The mechanism self-adjusts to secure the sample cartridge, reducing user burden while maintaining reliability

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The carrier base is pre-configured with the retainer mechanism and cooler block before sample transfer. This preliminary preparation ensures that when the sample cartridge is introduced, it is immediately secured and cooled without requiring precise real-time operations by the user

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Ensures stable cooling and safe carriage of sample cartridges, reducing user burden by eliminating the need for precise operations and maintaining the cooled condition from processing to observation.

Implementation Method 1

a cooler block configured to be cooled via the sub stage

Methodology Applied
Scientific EffectCooling: Cooling

Data Source

PatentUS12451337B2Sample cartridge carrier apparatus and carrier base
Publication Date: 2025.10.21 JEOL LTD
  • US12451337B2 patent drawing
  • US12451337B2 patent drawing
  • US12451337B2 patent drawing

AI summary

A sample cartridge carrier apparatus is coupled with a focused ion beam processing apparatus (FIB processing apparatus). A guide mechanism is configured to guide a series of movements of a sample cartridge holder to allow a sample cartridge to be held by a carrier base on a sub stage. Sub cooling equipment is configured to cool the sample cartridge via the sub stage. A carrier mechanism carries the carrier base between the sub stage and a main stage.