Sample Collection Device with Segmented Active Surface

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Solution Overview

Problem

Current sample collection devices face challenges in efficiently collecting and analyzing small quantities of biological, environmental, and chemical samples, often requiring additional steps for sample extraction and concentration due to large undefined surface areas and the need for chemical extraction before identification can be made.

Innovation Solution

A sample collection device with an active collection component detachably connected to a handling component, featuring a smaller active collection surface area that concentrates samples from a substrate, allowing for direct analysis without additional transfer steps, using materials like Whatman paper and securing elements for attachment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If a large undefined surface area is used for sample collection, then the collection area is sufficient, but the sample concentration is insufficient and additional extraction steps are required

Engineering Contradiction:
Improvesample concentrationVSAvoidcollection process steps
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The collection device is divided into two distinct portions: a first portion with a large surface area for initial sample collection from the substrate, and a second portion with a smaller surface area for sample concentration and analysis. This segmentation allows the device to perform multiple functions in a single integrated structure, eliminating the need for separate collection and concentration steps.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention transitions from a single large two-dimensional collection surface to a multi-dimensional structure with portions of different surface areas. The first portion provides broad coverage for sample acquisition, while the second portion provides intensified concentration area, effectively adding a dimensional aspect to the collection process.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Productivity

If chemical extraction is performed before identification, then sample analysis is enabled, but the process time and complexity increase

Engineering Contradiction:
Improveidentification process efficiencyVSAvoidextraction and analysis time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The invention merges the sample collection function with the sample concentration function into a single integrated device. The first portion collects the sample while the second portion simultaneously concentrates it, eliminating the need for separate chemical extraction steps and reducing overall process time.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The device performs sample concentration as a preliminary action during the collection process itself. By concentrating the sample on the second portion during the same time frame as collection occurs on the first portion, the device prepares the sample for analysis without requiring additional time for separate concentration steps.

Inventive Principle:
Principle #10Preliminary action

3Quantity of substance

If the active collection surface area is made smaller, then sample concentration is improved, but the collection area is reduced

Engineering Contradiction:
Improvesample concentrationVSAvoidcollection surface area
Core Design Contradiction:
Quantity of substanceVSArea of stationary object

Solution Approach 1:

The collection surface is segmented into two portions with different area characteristics. The first portion has a large surface area optimized for comprehensive sample collection from the substrate, while the second portion has a smaller surface area optimized for concentrating and analyzing the collected sample. Each portion is optimized for its specific function rather than requiring a single compromise area.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables efficient collection and analysis of small sample quantities by concentrating samples onto a smaller active collection surface area, facilitating direct analysis and reducing the need for additional extraction steps, thereby improving the identification process.

Implementation Method 1

collect a sample from at least a first surface area of a substrate to the active collection surface area

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Data Source

PatentUS9719130B2Sample collection devices, kits and methods of use
Publication Date: 2017.08.01 LIFE TECHNOLOGIES CORP
  • US9719130B2 patent drawing
  • US9719130B2 patent drawing
  • US9719130B2 patent drawing

AI summary

Devices, methods, and kits are disclosed for collection, labeling and analysis of samples containing a substance of interest. Such devices and methods are used in forensic, human identification, access and importation control, and other investigative technologies to collect even limited amounts of a substance of interest that may be present on a substrate and to facilitate analysis to identify the substance of interest.