Integrated Sample Filtration Layout for Faster Purification
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Solution Overview
Problem
The existing process of clarification and purification of samples containing target substances is inefficient and prone to sample degradation due to being carried out in separate devices, leading to a slow and manual process.
Innovation Solution
A sample preparation system that integrates clarification and purification operations in a single device using a serial arrangement of means, valves, and a pump for automated fluid movement, allowing for efficient and fast processing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If clarification and purification are carried out in two separate devices with manual transfer, then each operation can be performed with dedicated equipment, but the process becomes slow and leads to sample degradation
Solution Approach 1:
The patent combines clarification and purification operations into a single integrated device with multiple processing chambers. The sample can undergo clarification in a first chamber and then purification in a second chamber without manual transfer, eliminating exposure to degradation while maintaining dedicated functionality for each operation type.
Solution Approach 2:
The integrated device enables continuous processing where the sample flows sequentially through clarification and purification chambers without interruption or manual handling. This continuous action prevents sample degradation that would occur during manual transfer between separate devices while maintaining high processing throughput.
2Ease of manufacture
If clarification and purification are performed in separate devices, then equipment can be optimized for each specific operation, but manual intervention is required leading to inefficiency
Solution Approach 1:
The integrated device incorporates multiple processing chambers within a single system that can perform different operations (clarification, purification, or both sequentially). Each chamber can be optimized for its specific function while the overall system provides automated multi-functional capability, eliminating the need for manual transfer between separate specialized devices.
Solution Approach 2:
The patent merges multiple specialized operations into one automated device where clarification and purification chambers work in sequence. The system maintains the specialized functionality of each operation type while automating the entire process flow, removing manual intervention requirements.
3Device complexity
If manual transfer between clarification and purification devices is used, then equipment complexity can be reduced, but the process becomes inefficient and time-consuming
Solution Approach 1:
The patent integrates multiple processing chambers into a single device with interconnected fluid pathways. This merging eliminates the need for manual transfer between separate devices, significantly reducing processing time while the modular chamber design keeps the overall system structure manageable and not excessively complex.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The integrated system enables fast and efficient clarification and purification of samples, reducing sample degradation and manual labor, while yielding a well-defined output for further analysis.
Implementation Method 1
a pump configured to move fluid within the sample preparation system
Implementation Method 2
a first filter configured to clarify the sample to be purified
Implementation Method 3
a second filter configured to purify the clarified sample
Data Source
AI summary
A sample preparation system includes a serial arrangement of a first means configured to being connected to a first consumable and a second means configured to being connected to a second consumable, and a first valve arranged between the first means and the second means, and a second valve arranged downstream of the second means. A first line provides fluidic communication between the first means and the first valve, a second line provides fluidic communication between the first valve and the second valve via the second means, and a third line provides fluidic communication directly between the first valve and the second valve configured to bypass the second means.