Sample Holder Transfer Mechanism for Automatic Carrier Release
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Solution Overview
Problem
Existing sample holder transfer devices in cryo-microscopy require manual operation to open and close the sample carrier fixing element, complicating the process of inserting and removing sample carriers, which can lead to handling inefficiencies.
Innovation Solution
A sample holder transfer device with a switching mechanism that automatically switches the sample carrier fixing element between open and closed positions, allowing for simplified insertion and removal of sample carriers without manual operation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If manual operation is used to open and close the sample carrier fixing element, then the device structure remains simple, but the handling efficiency decreases and operational complexity increases
Solution Approach 1:
The sample carrier fixing element is designed to automatically open and close through spring-loaded mechanisms and cam-actuated release systems. When the sample holder is inserted or removed, the fixing element self-activates to secure or release the sample carrier without requiring manual intervention, thereby improving handling efficiency while maintaining relatively simple device structure
Solution Approach 2:
The fixing element is pre-configured with spring-loaded arms and cam surfaces that are ready to engage or disengage the sample carrier at the appropriate moments. The spring arms are预先 positioned to clamp the sample carrier when the holder is inserted, and the cam mechanism is pre-set to release them when removal is needed, enabling automatic operation without complex control systems
2Ease of operation
If manual manipulation of the sample carrier fixing element is required, then the device complexity remains low, but the ease of operation deteriorates due to complicated insertion and removal processes
Solution Approach 1:
The fixing element automatically performs the clamping and releasing actions through spring-loaded arms that engage with the sample carrier when the holder is inserted, and release when a cam mechanism is actuated during removal. This self-service mechanism eliminates the need for manual manipulation of screws, clips, or other fastening devices, significantly improving ease of operation
Solution Approach 2:
The fixing element incorporates spring-loaded arms that dynamically adjust their clamping force and position based on the insertion depth and orientation of the sample carrier. The cam-actuated release mechanism provides dynamic control over the releasing action, allowing smooth and easy removal without requiring excessive force or complex manual operations
Data Source
AI summary
A sample holder transfer device is for use in cryo-microscopy and for transferring a sample holder to an analysing or processing unit. The sample holder is configured for holding a sample carrier carrying a sample. The sample holder transfer device is configured to receive the sample holder, the sample holder including a sample carrier fixing element. At least one section of the sample carrier fixing element is configured, when in a first position, to fix the sample carrier to the sample holder, and, when in a second position, to release the sample carrier or provide access to an area where the sample carrier is to be placed. The sample holder transfer device includes a switching mechanism operable to switch the at least one section of the sample carrier fixing element of the sample holder from the first to the second position or from the second to the first position.