Sample Injection Device with Configurable Solvent Cleaning Order

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Solution Overview

Problem

Conventional sample injection devices for gas chromatography have a fixed cleaning order for multiple solvents, limiting the degree of freedom in cleaning, which can result in reduced cleaning effectiveness and increased carryover of samples.

Innovation Solution

A sample injection device that allows for customizable cleaning order settings based on solvent polarity and user preferences, enabling the use of solvents with high cleanliness before sample injection and adjusting the number of cleaning cycles based on sample viscosity, with automatic settings possible through pre-stored candidate substance information.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a fixed cleaning order of multiple cleaning solvents is used, then the device operation is simple, but the cleaning effectiveness is reduced and carryover increases

Engineering Contradiction:
Improvecleaning effectivenessVSAvoidcleaning order setting complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The cleaning order is made dynamically adjustable rather than fixed. The system allows users to freely set and change the cleaning order of multiple cleaning solvents according to different cleaning needs, transforming a static fixed-order system into a dynamic configurable system that adapts to various cleaning requirements.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The cleaning order parameter is made changeable. The system enables modification of the sequence in which multiple cleaning solvents are applied, allowing optimization of cleaning effectiveness by adjusting this parameter based on the specific cleaning task, sample type, and solvent properties.

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If cleaning order is fixed, then the device is easy to operate, but the degree of freedom in setting cleaning is limited

Engineering Contradiction:
Improvecleaning order flexibilityVSAvoidoperation simplicity
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The system provides dynamic configurability for cleaning order while maintaining ease of operation through automated functions. Users can freely adjust the cleaning sequence when needed, but the system also offers automatic cleaning order determination based on sample and solvent properties, balancing flexibility with operational simplicity.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system performs self-service by automatically determining the optimal cleaning order based on pre-stored information about sample properties and solvent characteristics. This eliminates the need for users to manually configure the cleaning sequence in routine cases, maintaining ease of operation while providing adaptability when manual adjustment is required.

Inventive Principle:
Principle #25Self-service

3Object-generated harmful factors

If cleaning solvent with high cleanliness is used immediately before injection, then carryover is reduced, but the cleaning order must be flexible

Engineering Contradiction:
ImprovecarryoverVSAvoidcleaning order configuration
Core Design Contradiction:
Object-generated harmful factorsVSDevice complexity

Solution Approach 1:

The cleaning order parameter can be changed to place the cleaning solvent with highest cleanliness immediately before sample injection. This parameter adjustment ensures that the most effective cleaning occurs at the critical moment before injection, minimizing carryover while the system manages the configuration complexity.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system performs preliminary cleaning actions using multiple solvents in an optimized sequence, with the final cleaning solvent selected and positioned to provide maximum cleanliness immediately before injection. This preliminary multi-stage cleaning approach ensures minimal carryover by preparing the syringe thoroughly beforehand.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS11802853B2Sample injection device and sample injection system
Publication Date: 2023.10.31 SHIMADZU CORP
  • US11802853B2 patent drawing
  • US11802853B2 patent drawing
  • US11802853B2 patent drawing

AI summary

A sample injection device is provided with a syringe for injecting a sample and an arrangement unit in which plural kinds of cleaning solvents are arranged to clean the syringe. The device is configured to be able to set a cleaning order of the syringe by the plural kinds of cleaning solvents.