Sample Analysis Interference Detection Using Dual Photoelectric Data
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Solution Overview
Problem
Existing sample analysis systems face challenges in accurately identifying and removing interferences during detection, leading to reduced accuracy of detection results due to subjective manual methods that do not account for diverse interference sources.
Innovation Solution
A sample analysis system that utilizes photoelectric data from both the to-be-detected sample and its reaction solution to determine interferent information, combining this data to identify and correct for interferences, thereby improving detection accuracy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If manual methods are used to identify interferences during detection, then the system is simple to operate, but the accuracy of detection results is reduced
Solution Approach 1:
The interference identification process is segmented into multiple independent detection stages: first detecting interferent information in the to-be-detected sample, then detecting interferent information in the reaction solution, and finally combining both results to determine the interferent source. This segmentation allows each detection stage to focus on specific aspects, improving overall accuracy without requiring a single complex system.
Solution Approach 2:
The system performs preliminary detection of interferent information in the to-be-detected sample before the actual detection process. By identifying potential interferences in advance and comparing them with interferent information from the reaction solution, the system can proactively correct for interferences, thereby improving detection accuracy without adding significant complexity to the main detection workflow.
2Reliability
If multiple detection methods are combined to identify interferences, then the accuracy of interferent identification is improved, but the device complexity increases
Solution Approach 1:
The detection device is designed with multi-functionality to detect both the to-be-detected sample and the reaction solution using the same optical detection system. The light source component and optical signal detector can switch between different detection modes and wavelengths, enabling a single device to perform multiple detection functions without requiring separate specialized equipment for each detection type, thus improving reliability while controlling complexity.
Solution Approach 2:
The control device integrates feedback mechanisms that automatically process and compare interferent information from both detection stages. The system uses feedback loops to analyze the combination of interferent information, determine the interferent source, and apply corrections to the detection results. This automated feedback processing improves reliability by reducing manual intervention while managing system complexity through integrated control algorithms.
3Measurement precision
If interferent detection is performed on both the sample and reaction solution, then the precision of interferent source determination is improved, but the detection time is increased
Solution Approach 1:
The system merges the detection of interferent information from both the to-be-detected sample and the reaction solution into a unified analysis process. The control device combines both sets of interferent information to determine the interferent source, allowing the system to leverage data from multiple stages without requiring separate, time-consuming analysis procedures. This merging approach improves precision while minimizing additional time requirements.
Solution Approach 2:
The detection process maintains continuity by performing interferent detection on the reaction solution immediately after the initial sample detection, without interrupting the overall workflow. The system continuously accumulates interferent information from both stages and processes them together, ensuring that the useful action of detection continues uninterrupted, thereby improving precision without significant time penalty.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system provides a more reliable basis for interference removal by objectively determining interferent types and sources, enhancing the precision of detection results.
Implementation Method 1
The light source component is configured to generate an irradiation light, the irradiation light forms an emission light after irradiating the reaction vessel, and the optical signal detector acquires the emission light to obtain photoelectric data
Data Source
Figure 1~2A
Figure 2B
Figure 3A
AI summary
In a sample analysis system and method provided in embodiments of the invention, on one hand, interferent information in a to-be-detected sample may be obtained based on photoelectric data of the to-be-detected sample or a mixed solution of the to-be-detected sample; on the other hand, interferent information in a reaction solution may be obtained based on photoelectric data of the reaction solution of the to-be-detected sample; and an interferent type or interferent source in the reaction solution may be determined based on a combination of the two types of interferent information. Compared to a method for determining interferences by manually observing sample states, the technical solution of each of the embodiments of the invention may eliminate impacts of subjective factors and provide more diverse and comprehensive information for determining the interferences, thereby providing a more reliable basis for removing the interferences and further improving accuracy of the detection result of the sample.