Sample Liquid Preparing Apparatus Uniform Mixing Control
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Solution Overview
Problem
Conventional sample liquid preparing apparatuses experience inconsistent sample concentration during injection, leading to non-uniform mixing with reagents in test cartridges, which can result in incorrect test results due to varying reagent elution rates throughout the process.
Innovation Solution
The apparatus includes a first cylinder portion with plugs and a cap portion that uses a plunger and fixing mechanisms to control the flow of sample process liquid, ensuring uniform mixing by adjusting the volume of the sample liquid mixture and maintaining consistent reagent elution through a bypass channel and capillary action.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If a large amount of sample elutes into the sample process liquid in the early phase of injection, then the sample concentration is high in the early phase, but the sample concentration gradually decreases toward the final phase
Solution Approach 1:
The patent changes the physical parameters of the sample process liquid by adjusting its viscosity through formulation. By controlling the viscosity to be within a specific range (1 cP to 10 cP), the liquid ensures consistent flow characteristics throughout the injection process, maintaining uniform sample concentration from early to final phases
2Reliability
If the liquid mixture is not uniformly mixed and the first reagent does not uniformly elute into the liquid mixture, then the test result may be incorrect, but uniform mixing and elution are difficult to achieve
Solution Approach 1:
The patent optimizes the viscosity parameter of the sample process liquid to achieve uniform mixing and reagent elution. By controlling viscosity within the specific range, the liquid ensures consistent flow and mixing characteristics, leading to uniform reagent distribution and reliable test results without requiring complex mixing mechanisms
Solution Approach 2:
The sample process liquid performs self-mixing and self-elution functions through its controlled viscosity properties. The liquid automatically ensures uniform distribution of sample and reagent without requiring external mechanical mixing devices or complex elution control systems
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This design ensures uniform mixing of the sample with the sample process liquid and subsequent uniform elution of reagents, promoting accurate reactions and preventing incorrect test results by maintaining consistent sample concentration and reagent distribution.
Implementation Method 1
The liquid mixture passes through the filter provided in the test cartridge. With this operation, the first reagent elutes into the liquid mixture. The reaction liquid which has reacted with the liquid mixture and the first reagent moves on the strip by a capillary action.
Implementation Method 2
When the liquid mixture is injected into the test cartridge, the liquid mixture passes through the filter provided in the test cartridge. With this operation, the first reagent elutes into the liquid mixture.
Data Source
AI summary
A sample liquid preparing apparatus includes a first cylinder portion, a cap portion, and a liquid preparation vessel. The first cylinder portion has a first to-be-fixed portion and a second to-be-fixed portion. The first cylinder portion accommodates a first plug and a second plug. A liquid is sealed between these plugs. The cap portion includes a plunger portion to push the second plug and a first fixing portion to limit the plunger portion from pushing the second plug by fixing the first to-be-fixed portion. The liquid preparation vessel includes a second cylinder portion whose internal space is pressed by the first cylinder portion and a second fixing portion to limit the first cylinder portion from pushing by fixing the second to-be-fixed portion.