Automated Sample Processing System Barcode Tracking

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Solution Overview

Problem

Current automated and semi-automated sample processing systems are labor-intensive, prone to operator error, and inefficient, often requiring manual labor and pre-processing steps, with limitations in accepting various sample formats and processing different types of samples simultaneously.

Innovation Solution

An automated sample processing system that includes a central control unit, barcode reader, shaker unit, decapper/capper unit, and aspirator/reagent pump, capable of processing multiple samples in parallel through a standardized protocol, reducing manual labor and increasing throughput by handling various sample formats and types simultaneously.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual or semi-automated methods are used for sample processing, then operator control and flexibility are maintained, but labor intensity increases and operator error becomes more likely

Engineering Contradiction:
Improveoperator error rateVSAvoidautomation level
Core Design Contradiction:
ReliabilityVSExtent of automation

Solution Approach 1:

The system enables self-service operation through automated sample intake, barcode scanning, and processing. Samples are automatically recognized, tracked, and processed through the workflow without requiring manual intervention at each step, reducing operator error while maintaining high automation levels

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system implements feedback mechanisms through barcode tracking that continuously monitors sample status and provides real-time information about sample location and processing state. This feedback loop ensures accurate sample identification and tracking throughout the automated process, preventing operator errors

Inventive Principle:
Principle #23Feedback

2Productivity

If semi-automated systems are used, then some automation is achieved, but pre-processing steps still require manual labor and system complexity increases

Engineering Contradiction:
Improvesample processing throughputVSAvoidsystem complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system employs universal sample containers with standardized barcodes that can accommodate multiple sample types and formats. The single vial design serves multiple functions: sample storage, identification, and processing container, eliminating the need for multiple specialized containers and reducing overall system complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system segments the sample processing workflow into distinct automated stages: sample intake with barcode scanning, automated processing, and result generation. Each stage is independently automated but integrates seamlessly into the overall workflow, increasing productivity without proportionally increasing complexity

Inventive Principle:
Principle #1Segmentation

3Adaptability or versatility

If existing automated systems are used, then throughput is increased, but they cannot accept various sample formats and cannot process different sample types simultaneously

Engineering Contradiction:
Improvesample format acceptanceVSAvoidprocessing throughput
Core Design Contradiction:
Adaptability or versatilityVSProductivity

Solution Approach 1:

The system uses universal sample containers with barcodes that can identify and accommodate different sample types (urine, blood, tissue, etc.) and formats. The standardized container design with machine-readable codes enables the system to handle diverse samples through a single interface, maintaining high throughput while improving adaptability

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system changes parameters through barcode identification, where different barcode patterns encode different sample types and required processing protocols. This parameter encoding allows the system to automatically adjust processing parameters based on sample type while maintaining consistent automated handling, thereby supporting both versatility and throughput

Inventive Principle:
Principle #35Parameter changes

4Loss of time

If manual pre-processing steps are required, then sample preparation flexibility is maintained, but processing time increases and productivity decreases

Engineering Contradiction:
Improveprocessing timeVSAvoidthroughput
Core Design Contradiction:
Loss of timeVSProductivity

Solution Approach 1:

Samples are pre-labeled with barcodes before entering the system, and the system performs automated sample adequacy assessment and preparation upon intake. This preliminary automated action eliminates the need for manual pre-processing steps later in the workflow, reducing processing time and increasing throughput

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system maintains continuous automated processing through uninterrupted workflow stages. Samples move continuously from intake through processing without manual intervention pauses, ensuring that the useful action of sample processing occurs without interruption, thereby minimizing processing time and maximizing throughput

Inventive Principle:
Principle #20Continuity of useful action

Data Source

PatentEP2356469B1Open platform automated sample processing system
Publication Date: 2019.09.04 BECTON DICKINSON & CO
  • EP2356469B1 patent drawingFigure 1
  • EP2356469B1 patent drawingFigure 2
  • EP2356469B1 patent drawingFigure 3

AI summary

An automated sample processing system having a sample input adapted to simultaneously receive a number of sample containers, a reagent input adapted to receive one or more new reagent supplies, a consumable input adapted to receive one or more new consumable supplies, a solid waste output adapted to receive used consumable supplies, a liquid waste output adapted to receive one or more used reagent supplies, and a processing center. The processing center includes a decapper adapted to remove a lid from at least one sample container, an aspirator adapted to remove a specimen from the at least one sample container and transfer the specimen to an output vessel, and a capper adapted to replace the lid on the at least one sample container. The system also includes a sample output adapted to receive the output vessel, and a user interface adapted to receive an input from the user to indicate the identity of the at least one sample container, and control at least one operation based on a physical property of the at least one sample container.