Sample Receiving Block Surface Treatment for Laser Speckle Microbial Detection
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Solution Overview
Problem
Conventional methods for measuring bacteria or microbes require complex optical systems, specialized knowledge, and laboratory-level facilities, and are time-consuming.
Innovation Solution
A test sample receiving block and microbial detection apparatus that uses laser speckles to quickly sense the motion of bacteria or microbes by emitting light and detecting speckles, with a surface-treated sample receiving block to enhance light reflection and a controller for real-time analysis.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional optical techniques (Raman spectrometry, multispectral imaging) are used to measure bacteria or microbes, then measurement precision can be achieved, but device complexity and difficulty of operation increase significantly
Solution Approach 1:
The patent extracts only the essential measurement function from complex optical systems. Instead of using full Raman spectrometry or multispectral imaging systems, it isolates the core capability of detecting light scattering from bacterial motion, implementing it through a simple laser source and camera setup that eliminates unnecessary optical components while maintaining measurement effectiveness
Solution Approach 2:
The patent uses laser speckle patterns as an optical copy or representation of bacterial motion. Rather than directly measuring bacterial properties with complex optics, it captures the speckle pattern generated by coherent light scattering off moving bacteria, which serves as a simplified optical signature that can be analyzed to infer bacterial activity and antibiotic susceptibility
2Measurement precision
If conventional optical techniques are used for microbial measurement, then specific microbe types can be precisely measured, but measurement time increases
Solution Approach 1:
The patent employs time-lapse imaging with periodic capture of laser speckle patterns at multiple time points. By taking snapshots at intervals (e.g., every few seconds or minutes) and analyzing the temporal evolution of speckle patterns, it can precisely measure bacterial motion dynamics and antibiotic effects without requiring continuous measurement, thus reducing total measurement time while maintaining precision
Solution Approach 2:
The patent rushes through the measurement process by using rapid laser speckle capture and analysis. Instead of slow conventional optical methods, it quickly captures speckle patterns and processes them to determine bacterial susceptibility, compressing what would traditionally be a lengthy measurement into a rapid assessment
3Measurement precision
If conventional optical systems are used, then measurement capability is achieved, but ease of operation deteriorates due to specialized knowledge requirements
Solution Approach 1:
The patent implements self-service through automated laser speckle analysis. The system automatically captures images, processes the speckle patterns, and generates measurements of bacterial motion and antibiotic susceptibility without requiring user intervention or interpretation. This automation eliminates the need for specialized knowledge while maintaining measurement capability
Solution Approach 2:
The patent replaces complex mechanical optical systems with a simplified electronic imaging approach. By substituting intricate optical components and manual adjustment mechanisms with a digital camera and software-based speckle analysis, it eliminates the need for specialized operational knowledge while preserving measurement precision
4Ease of manufacture
If sample receiving block surface is left untreated, then manufacturing simplicity is maintained, but light reflection uniformity and measurement consistency deteriorate
Solution Approach 1:
The patent changes the surface parameter of the sample receiving block by applying a reflective coating or treatment. This modifies the surface optical properties to enhance light reflection uniformity, ensuring consistent illumination and speckle pattern generation across the sample area, which improves measurement reliability without significantly complicating the manufacturing process
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables rapid detection of bacterial susceptibility to antibiotics with reduced complexity and expertise, using a compact, user-friendly system that minimizes measurement time and deviation.
Implementation Method 1
a sensor module configured to detect a speckle generated when the emitted light is scattered by motion of bacteria or microbes contained in the sample
Implementation Method 2
the sample receiving block is surface-treated to increase an optical path of light reaching the sensor module when the emitted light is reflected or scattered by the sample accommodated in the sample groove portion
Data Source
AI summary
The present invention relates to a test sample receiving block and a microbial detection apparatus using the same. The test sample receiving block may include a sample receiving block having a sample groove portion formed therein, the sample groove portion containing the sample so that a light emission module emits light to the sample and a sensor module can detect a speckle generated when the emitted light is scattered by motion of bacteria or microbes contained in the sample, wherein the sample receiving block is surface-treated to increase an optical path of light reaching the sensor module when the emitted light is reflected or scattered by the sample accommodated in the sample groove portion, so that a pattern is formed on a surface of the sample groove portion.