Sample Separation Unit Mounting for Reliable Fluid Coupling

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Solution Overview

Problem

The mounting of a sample separation unit in a sample separation device, such as a chromatography column, is inconvenient and prone to errors due to the handling of small and unwieldy components, requiring special expertise.

Innovation Solution

A mounting device with an actuation unit and fluid coupling mechanism that allows users to easily transfer the sample separation unit from an accessible position to a fluid coupling position, forming a force-loaded fluidic coupling without manual handling of capillaries or fittings.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual handling of capillaries and fittings is used for mounting the sample separation unit, then the fluidic coupling can be formed, but the operation becomes inconvenient and error-prone requiring special expertise

Engineering Contradiction:
Improveease of mountingVSAvoidmounting reliability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The mounting device enables self-service mounting where the sample separation unit automatically performs the fluidic coupling action when inserted into the mounting device. The unit itself completes the connection without requiring external manual handling of capillaries or fittings, making the process both easy and reliable

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The mounting device acts as an intermediary mechanism between the user and the fluidic coupling process. It provides a user-friendly interface that translates simple insertion motion into reliable fluidic connection, eliminating the need for complex manual manipulation while ensuring consistent coupling quality

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If manual handling of small components is used for mounting, then the fluidic coupling can be established, but the process becomes time-consuming and complex

Engineering Contradiction:
Improvemounting speedVSAvoidmounting process complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The mounting device is pre-configured with all necessary coupling mechanisms and positioning elements in place before the sample separation unit is inserted. This preliminary arrangement eliminates the need for step-by-step manual assembly of capillaries and fittings, enabling rapid insertion and automatic coupling

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The mounting device merges multiple functions into a single integrated mechanism: positioning, alignment, and fluidic coupling are combined into one action. The sample separation unit performs all coupling operations simultaneously during insertion, reducing both time and complexity compared to manual multi-step assembly

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If force-loaded fluidic coupling is used, then the fluid connection reliability under high pressure is improved, but the mounting mechanism becomes more complex

Engineering Contradiction:
Improvefluid connection reliabilityVSAvoidcoupling mechanism complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The coupling mechanism utilizes dynamic forces generated during the insertion process itself. As the sample separation unit is pushed into the mounting device, kinetic energy is converted into coupling force that automatically engages the fluidic connections. This dynamic approach eliminates the need for complex static coupling mechanisms while ensuring reliable high-pressure connections

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables rapid, error-robust, and user-friendly mounting of the sample separation unit, ensuring a precise separation result with a reliable fluid connection that withstands high pressures, eliminating the need for specialized skills.

Implementation Method 1

a fluid coupling mechanism which is configured for forming a force-loaded fluidic coupling between the first fluid port and the first fluid connection point

Methodology Applied
Scientific EffectMechanical Force: Mechanical Force

Data Source

PatentUS12487213B2Mounting device for mounting a sample separation unit
Publication Date: 2025.12.02 AGILENT TECHNOLOGIES INC
  • US12487213B2 patent drawing
  • US12487213B2 patent drawing

AI summary

An installation device is for installing a sample separating device for separating a liquid sample in a sample separating tool. The installation device includes a first fluid connection for fluidically connecting to a first fluid connection point of the sample separating device, and an actuation device that can be actuated by a user for converting between an access position and a fluid coupling position. The access position makes the sample separating device accessible to the user, and the fluid coupling position fluidically couples the sample separating device. The installation device also includes a fluid coupling mechanism, which forms a force-loaded fluidic connection between the first fluid connection and the first fluid connection point when the sample separating device is converted into the fluid coupling position by the actuation device. The sample separating device may, for example, be configured for chromatography.