Sample Vial Filter Insert for Complete Dissolution and Clean Analysis

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Solution Overview

Problem

Existing analytical systems face challenges in efficiently analyzing solid samples that are poorly soluble or require external stressors, leading to costly and time-intensive experimentation, and there is a need for high-throughput analysis of liquid samples without contamination or clogging.

Innovation Solution

The use of filter inserts within sample vials that allow for the dissolution of solid samples in solvent, enabling direct analysis by automated systems, with features like hydrophobic or hydrophilic materials to selectively filter compounds and prevent contamination, and integration with analytical devices for efficient sample extraction.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of time

If solid samples are analyzed directly without complete dissolution, then analysis time is reduced, but analysis accuracy deteriorates due to incomplete solubilization

Engineering Contradiction:
Improveanalysis timeVSAvoidanalysis accuracy
Core Design Contradiction:
Loss of timeVSMeasurement precision

Solution Approach 1:

The filter insert is placed in the vial before sample dissolution, performing preliminary filtration preparation. This allows solid samples to be dissolved and filtered simultaneously during the automated analysis process, eliminating the need for separate filtration steps and enabling complete solubilization without extending analysis time.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The filter insert acts as an intermediary component between the solid sample and the analytical system. It mediates the dissolution process by providing a filtration interface that allows complete solubilization of solid samples while preventing undissolved particles from reaching the analytical system, thus maintaining both analysis speed and accuracy.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If filter inserts are added to sample vials, then sample filtration and contamination prevention are improved, but device complexity increases

Engineering Contradiction:
Improvecontamination preventionVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The filter insert combines multiple functions into a single component: filtration, contamination prevention, and automated sample extraction interface. By merging these functions into one integrated device that fits standard vial configurations, the system achieves improved reliability without proportionally increasing complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The filter insert is designed with universal compatibility with standard sample vials and automated analysis systems. Its multi-functional design allows it to serve as a filtration barrier, contamination preventor, and sample extraction interface simultaneously, reducing the need for additional specialized components.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Manufacturing precision

If manual sample preparation processes are used for solid samples, then complete dissolution can be achieved, but productivity decreases due to time-intensive experimentation

Engineering Contradiction:
Improvedissolution completenessVSAvoidthroughput
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The filter insert enables the sample preparation system to serve itself by providing automated filtration and extraction capabilities. Solid samples dissolve completely during the automated process without requiring manual intervention, and the filter insert automatically prevents particulate contamination, allowing high-throughput analysis with complete dissolution.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The filter insert replaces manual mechanical filtration and sample transfer operations with an automated system. The insert's design allows automated syringes or dispensing mechanisms to extract filtered sample solutions directly, eliminating the need for manual filtration and transfer steps while maintaining complete dissolution.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Facilitates rapid and efficient analysis of solid samples by ensuring complete dissolution and prevents contamination, reducing the need for costly and time-consuming manual processes, while allowing high-throughput analysis in automated systems.

Implementation Method 1

a filter assembly coupled with the distal end of the cylindrical body

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 2

features like hydrophobic or hydrophilic materials to selectively filter compounds

Methodology Applied
Scientific EffectHydrophobic filtering: Hydrophobe

Implementation Method 3

features like hydrophobic or hydrophilic materials to selectively filter compounds

Methodology Applied
Scientific EffectHydrophilic filtering: Hydrophile

Data Source

PatentUS20250222377A1Filter insert and sample vial using the same
Publication Date: 2025.07.10 REACTION ANALYTICS INC
  • US20250222377A1 patent drawing
  • US20250222377A1 patent drawing
  • US20250222377A1 patent drawing

AI summary

A filter insert, a sample vial incorporating a filter insert, a method of using a sample vial containing a filter insert for chemical analysis, and a sample vial kit including a filter insert. The filter insert includes a cylindrical body having a proximal end, a protrusion extending radially from the proximal end of the cylindrical body and configured to set on the open end of a sample vial, a distal end, a cavity extending longitudinally through the cylindrical body from the proximal end to the distal end, and a filter assembly coupled with the distal end of the cylindrical body.