Automated Sample Workcell Centrifuge Protocol Management
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Solution Overview
Problem
Current automated sample workcell systems are not flexible enough to simultaneously centrifuge samples requiring different centrifugation protocols, leading to longer processing times and increased costs due to the need for multiple centrifuges.
Innovation Solution
A method and system that assign centrifugation parameters to samples based on requested analyses, determine the centrifugation parameter of highest intensity, and centrifuge samples accordingly, allowing for the simultaneous processing of samples with different protocols in the same centrifuge.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If multiple centrifuges are used to process samples with different centrifugation protocols simultaneously, then processing time is reduced and productivity is improved, but device complexity and cost increase
Solution Approach 1:
The centrifuge is designed to handle multiple sample types with different centrifugation requirements (chemistry samples, coagulation samples, immunology samples) using a single device. The control system automatically adjusts centrifugation parameters based on sample type, making the centrifuge universal and eliminating the need for multiple specialized centrifuges.
Solution Approach 2:
The centrifuge operates dynamically by changing its centrifugation parameters (speed, time, acceleration) based on the specific requirements of the samples being processed. The control system allows real-time adjustment of centrifugation protocols to match different sample types, enabling flexible and adaptive processing.
2Device complexity
If samples with different centrifugation protocols are processed sequentially in a single centrifuge, then device complexity is reduced, but processing time increases and productivity decreases
Solution Approach 1:
Samples are pre-classified at the input station according to their centrifugation requirements before being loaded into the centrifuge. The control system receives advance information about sample types and prepares the appropriate centrifugation protocol in advance, enabling efficient batch processing without sequential delays.
Solution Approach 2:
The centrifuge maintains continuous operation by processing different sample types in batches according to their centrifugation requirements. The control system manages the workflow to minimize idle time, ensuring that the centrifuge is continuously productive by loading appropriate sample batches without unnecessary interruptions or waiting periods.
3Device complexity
If a single centrifuge processes all sample types, then cost is reduced and device complexity is lowered, but the ability to handle diverse centrifugation needs simultaneously is limited
Solution Approach 1:
The centrifuge's operational parameters (centrifugal force, rotation speed, processing time, acceleration rates) are dynamically changed based on the sample type being processed. The control system stores multiple centrifugation protocols and automatically selects and applies the appropriate parameters for chemistry samples, coagulation samples, immunology samples, or other sample types, providing full versatility within a single device.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach reduces the number of centrifuges required, decreases processing time, and lowers costs by enabling efficient handling of diverse centrifugation needs within a single centrifuge.
Implementation Method 1
a centrifuge operable to centrifuge a plurality of samples according to a centrifugation protocol
Data Source
AI summary
Illustrative embodiments of automated sample workcells and methods of operation are disclosed. The methods may include receiving a first plurality of samples, each of the first plurality of samples being linked to a requested analysis selected from among a plurality of analysis types; assigning at least one centrifugation parameter to each of the first plurality of samples in response to the requested analysis linked to that sample; loading a second plurality of samples into a centrifuge, the second plurality of samples being selected from among the first plurality of samples and comprising samples that have been assigned at least two different centrifugation parameters; determining a centrifugation parameter of highest centrifugation intensity from among the at least two different centrifugation parameters assigned to samples in the second plurality of samples; and centrifuging the second plurality of samples according to a centrifugation protocol comprising the centrifugation parameter of highest centrifugation intensity.


