Sampling Platform with 3D-Printed Ionization for Bulk Solids
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Solution Overview
Problem
Existing sampling technologies face challenges in efficiently detecting and identifying analytes in bulk solids, particularly in laboratory-based and field conditions, with a need for improved high-throughput sample analysis systems that can be coupled with portable mass spectrometers.
Innovation Solution
A sampling platform apparatus and system utilizing 3D-printed cone spray ionization mass spectrometry (3D-PCSI-MS) sources, which removably hold sample collection devices made of conductive polymers, such as those containing carbon nanotubes and polymers, and are configured to work with a motorized rotary disc platform for automated sample analysis, applying high voltage and solvent extraction to analyze solid media samples.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If existing sampling technologies are used for detecting analytes in bulk solids, then the analysis can be performed, but the throughput and efficiency are insufficient in both laboratory and field conditions
Solution Approach 1:
The sampling system is divided into multiple receptacles arranged in a circular array, with each receptacle holding a separate sample collection device. This segmentation allows parallel processing of multiple samples, increasing throughput while keeping each individual receptacle simple in design.
Solution Approach 2:
The sampling platform is designed to work with portable mass spectrometers and can analyze multiple types of samples (bulk solids, liquids, gases) using the same basic apparatus. The system provides multi-functionality across different sample types and analysis conditions, improving productivity without requiring separate complex systems for each application.
2Measurement precision
If high voltage is applied to sample collection devices for spray ionization, then analyte detection is enabled, but alignment precision between the distal end and mass spectrometer inlet is required
Solution Approach 1:
The sample collection devices are made from conductive materials (such as carbon nanotubes) specifically at the distal end where high voltage is applied. This localized conductive property enables spray ionization and analyte detection while the overall device structure can be manufactured with standard precision using 3D printing techniques.
Solution Approach 2:
The conductive sample collection device acts as an intermediary between the high voltage source and the sample matrix. The distal end of the device, which is in direct contact with the sample, serves as the interface for ionization, allowing precise control of the ionization zone while the device itself can be manufactured with conventional precision.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system enhances the detection and identification of analytes in bulk solids, achieving increased throughput and efficiency in both laboratory and field conditions by using a portable mass spectrometer, with improved alignment and solvent extraction capabilities.
Implementation Method 1
sample collection devices made of conductive polymers, such as those containing carbon nanotubes
Implementation Method 2
conductive polymers, such as those containing carbon nanotubes
Implementation Method 3
applying high voltage and solvent extraction to analyze solid media samples
Implementation Method 4
3D-printed cone spray ionization mass spectrometry (3D-PCSI-MS) sources
Data Source
AI summary
The embodiments are directed to both sampling apparatuses and systems. Apparatus embodiments are directed to a sample collection apparatus having several receptacles configured to removably-hold sample collection devices. The sample collection devices are configured to hold a sample including solid media and analyte. System embodiments include the sample collection apparatus and several receptacles for removably-holding sample collection devices. The system embodiments also include additional components to perform analysis of the sample.