Sapphire Microreactors for Extreme Conditions

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Solution Overview

Problem

Current microreactors face limitations in terms of temperature, pressure, and chemical compatibility, particularly in high-temperature and high-pressure applications, and lack transparency across a wide wavelength range for observation and analysis.

Innovation Solution

A transparent sapphire microreactor with monocrystalline or polycrystalline structure, optimized for extreme conditions, featuring microchannels etched in wafers that can withstand high temperatures and pressures, and allowing transmission from ultraviolet to infrared wavelengths, eliminating the need for intermediate layers and enabling efficient chemical and biochemical reactions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If traditional materials (polymers, glass, silicon-borosilicate) are used for microreactors, then ease of manufacture is improved, but temperature and pressure tolerance deteriorates

Engineering Contradiction:
Improveease of manufactureVSAvoidtemperature tolerance
Core Design Contradiction:
Ease of manufactureVSTemperature

Solution Approach 1:

The patent employs sapphire (crystalline alumina) as the microreactor material, representing a transition from conventional materials to advanced ceramic materials. Sapphire provides superior temperature and pressure resistance while maintaining optical transparency, resolving the contradiction between ease of manufacture and extreme condition tolerance through material science advancement.

Inventive Principle:
Principle #40Composite materials

2Ease of manufacture

If traditional materials (polymers, glass, silicon-borosilicate) are used for microreactors, then ease of manufacture is improved, but pressure tolerance deteriorates

Engineering Contradiction:
Improveease of manufactureVSAvoidpressure tolerance
Core Design Contradiction:
Ease of manufactureVSStress or pressure

Solution Approach 1:

Sapphire's exceptional mechanical strength and pressure resistance properties are utilized to construct the microreactor body. The crystalline structure of sapphire provides high structural integrity under extreme pressure conditions, overcoming the limitations of traditional polymer and glass materials while maintaining manufacturability through established ceramic processing techniques.

Inventive Principle:
Principle #40Composite materials

3Adaptability or versatility

If traditional materials are used for microreactors, then chemical compatibility is improved for common chemicals, but compatibility with extreme condition chemicals deteriorates

Engineering Contradiction:
Improvechemical compatibilityVSAvoidchemical compatibility in extreme conditions
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

Sapphire exhibits exceptional chemical inertness and resistance to corrosion from aggressive chemicals, particularly under high temperature and pressure conditions. This advanced material property ensures reliable operation with chemically demanding processes while maintaining the versatility needed for various chemical reactions.

Inventive Principle:
Principle #40Composite materials

4Temperature

If opaque materials (metal, ceramics) are used for microreactors, then temperature and pressure tolerance is improved, but transparency for observation deteriorates

Engineering Contradiction:
Improvetemperature toleranceVSAvoidtransparency
Core Design Contradiction:
TemperatureVSIllumination intensity

Solution Approach 1:

Sapphire uniquely combines the high temperature and pressure resistance of ceramics with optical transparency across multiple wavelengths (visible, UV, IR). This dual property enables real-time observation and spectroscopic analysis of reactions occurring under extreme conditions, eliminating the trade-off between durability and observability.

Inventive Principle:
Principle #40Composite materials

5Ease of operation

If intermediate layers are added to microreactor assembly, then assembly ease is improved, but chemical compatibility and transparency deteriorates

Engineering Contradiction:
Improveassembly easeVSAvoidchemical compatibility
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent employs direct bonding of sapphire components to create an intermediate-layer-free assembly. This approach eliminates potential chemical incompatibility and optical interference from sealing layers, while sapphire's inherent mechanical properties enable direct bonding through appropriate surface preparation and bonding protocols.

Inventive Principle:
Principle #5Merging (Combining)

6Temperature

If sapphire is used for microreactor, then temperature and pressure tolerance is improved, but manufacturing complexity increases

Engineering Contradiction:
Improvetemperature toleranceVSAvoidmanufacturing complexity
Core Design Contradiction:
TemperatureVSDevice complexity

Solution Approach 1:

The microreactor is designed as an integrated sapphire component with microchannels formed directly in the solid material. This segmentation approach consolidates multiple manufacturing steps into a unified fabrication process, reducing overall complexity despite the advanced material requirements.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The sapphire microreactor surpasses existing microreactors in temperature and pressure tolerance, provides transparent observation across a wide wavelength range, and ensures chemical compatibility, facilitating advanced chemical synthesis and analysis in extreme conditions.

Implementation Method 1

Sapphire has exceptional optical properties: it is transparent to light waves with wavelengths between 150 nm (ultraviolet) and 6500 nm (infrared)

Methodology Applied
Scientific EffectOptical transmission: Light

Implementation Method 2

Sapphire possesses excellent thermal conductivity

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Data Source

PatentEP4132701B1Sapphire microreactors
Publication Date: 2024.04.03 CENT NAT DE LA RECH SCI (C N R S)
  • EP4132701B1 patent drawingFigure 1~3
  • EP4132701B1 patent drawingFigure 4~5
  • EP4132701B1 patent drawingFigure 6A~6B

AI summary

The present invention concerns the field of microreaction devices and of micro-process engineering. It particularly involves devices having micro-channels (internal chambers with micrometric to submicrometric dimensions) for conveying chemical or biochemical mixtures and/or reactions. More specifically, such devices are optimised to achieve high temperature and pressure stresses (i.e. 500°C and 500 bar). For observation and analysis purposes, the microreaction devices have a wide range of transparency in terms of wavelengths. The subject matter of the present invention relates to a microfluid or microreactor device made of transparent sapphire, preferably in the wavelength range ranging from 150 to 6500 nm, and to its manufacturing method and to its use.