Scalp Care Composition Solvent Optimization
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Solution Overview
Problem
Current anti-dandruff leave-on treatments lack the efficacy and scalp benefits that can replace or complement rinse-off products, with soluble anti-dandruff actives often experiencing decreased solubility and stability issues due to insufficient solvent concentrations, leading to reduced anti-fungal activity.
Innovation Solution
A scalp care composition containing 0.3% to 2% anti-dandruff active, with climbazole soluble in a mixture of butylene glycol and benzyl alcohol solvents, along with additional hair growth stimulating agents and rheology modifiers, to enhance solubility and stability, thereby increasing anti-fungal potency.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If soluble anti-dandruff actives are used in leave-on treatments, then anti-dandruff efficacy is improved, but solubility and stability decrease due to insufficient solvent concentrations
Solution Approach 1:
The patent changes the concentration parameter of organic solvents from insufficient levels to optimized ranges (butylene glycol: 0.1-10%, benzyl alcohol: 0.1-5%). This parameter adjustment resolves the contradiction by providing enough solvent to maintain climbazole solubility and stability while preserving anti-fungal efficacy.
Solution Approach 2:
The patent uses a composite solvent system combining butylene glycol and benzyl alcohol with climbazole active ingredient. This composite formulation achieves both solubility enhancement and stability improvement, resolving the technical contradiction between efficacy and compositional stability.
2Stability of the object's composition
If higher concentrations of organic solvents are used to improve solubility, then solubility increases, but formulation complexity and potential irritation increase
Solution Approach 1:
The patent optimizes solvent concentration parameters to effective minimal levels (butylene glycol: 0.1-10%, benzyl alcohol: 0.1-5%) rather than using high concentrations. This resolves the contradiction by achieving sufficient solubility without excessive formulation complexity or potential irritation from high solvent loads.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition demonstrates a 10.5% increase in anti-fungal activity and improved solubility of climbazole, maintaining effective delivery and stability, as shown by zone of inhibition data, providing enhanced scalp benefits and efficacy.
Implementation Method 1
the soluble anti-dandruff active comprises climbazole from 0.1 to 25 weight % of one or more organic solvents by weight of the total composition, wherein the organic solvent comprises butylene glycol and benzyl alcohol
Implementation Method 2
the incorporation of certain formulation solvents can increase the anti-fungal potency of a given composition
Data Source
Figure 1
AI summary
A scalp care composition directed to a scalp care composition comprising from about 0.05% to about 5% of an anti-dandruff active, from about 0.1% to about 25% of one or more organic solvents, from about 1% to about 99% of a volatile carrier wherein the anti-dandruff active is soluble in the scalp care composition.