Scalp Neurostimulation Parameter Calibration Across Electrode Arrays

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Solution Overview

Problem

Existing neurostimulation treatments for peripheral and cranial nerves in the head region, particularly those targeting cephalic nerves under hair-covered areas, face challenges in effectively setting and calibrating treatment parameters, leading to invasive procedures with high complication rates and the need for user-specific and personalized settings.

Innovation Solution

A method for determining user-specific treatment parameter values for multi-channel transdermal neurostimulation, involving setting correlations between parameter values for different electrode arrays on the scalp, and calibrating these parameters through user inputs to ensure effective and comfortable stimulation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If implanted or percutaneous nerve stimulators are used to stimulate cephalic nerves under hair-covered regions, then effective nerve stimulation is achieved, but invasive procedures with high complication rates occur

Engineering Contradiction:
Improvenerve stimulation effectivenessVSAvoidcomplication rate
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent introduces transdermal electrodes as an intermediary device that delivers electrical stimulation through the scalp and hair without requiring surgical implantation. This mediator approach allows current to reach cephalic nerves through non-invasive transdermal application, avoiding the complications of implanted leads and pulse generators while maintaining therapeutic effectiveness

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces the mechanical surgical implantation process with a non-invasive transdermal electrical stimulation system. Instead of physically inserting electrodes and leads into the body, the system uses externally applied electrical fields that penetrate the scalp to stimulate nerves, substituting a mechanical invasive procedure with a field-based non-invasive approach

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If user-specific and personalized treatment parameters are set for transdermal neurostimulation, then treatment efficacy and user comfort are optimized, but complex parameter setting and calibration are required

Engineering Contradiction:
Improvetreatment efficacyVSAvoidparameter setting complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent implements feedback mechanisms where user responses to stimulation are used to automatically adjust and optimize treatment parameters. The system monitors user comfort and efficacy responses, then modifies current intensity, pulse duration, and frequency parameters accordingly, reducing the need for manual calibration while maintaining personalized optimization

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent enables the neurostimulation system to automatically determine and adjust its own treatment parameters based on user responses and pre-programmed algorithms. The device performs self-calibration by monitoring user feedback and autonomously optimizing stimulation settings, eliminating the need for complex manual parameter setting by healthcare providers

Inventive Principle:
Principle #25Self-service

Data Source

PatentEP4013485B1Methods for transdermal neurostimulation treatment
Publication Date: 2026.04.08 NEUROLIEF LTD
  • EP4013485B1 patent drawingFigure 1
  • EP4013485B1 patent drawingFigure 2A~2B
  • EP4013485B1 patent drawingFigure 3

AI summary

A method for determining treatment parameter values for transdermal neurostimulation treatments applied on a user's scalp comprises setting a first set of treatment parameter values for a first electrode-array engaged with a first portion of the user's scalp for administering electrical pulses thereto, for example according to a correlation that includes a direct relationship between at least one parameter value of said first set of treatment parameter values and a corresponding at least one parameter value of a set of user-specific sensory-threshold parameter values; and setting a second set of treatment parameter values for a second electrode-array engaged with a second portion of the user's scalp for administering electrical pulses thereto, according to another correlation that includes another direct relationship between at least one parameter value of said second set of treatment parameter values and said at least one parameter value of said first set of treatment parameter values.