Scanner Substrate Surface Detection via Optical Intermediary

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Solution Overview

Problem

Current systems for detecting substrate surfaces within scanners lack efficiency and accuracy, particularly in isolating target analytes from substrates such as well plates or slides, which hinders precise detection and analysis of biological samples.

Innovation Solution

A scanner system equipped with a picker tip and a position detection system that uses a z-picker motor system to locate and detect substrate surfaces by calculating differences in output voltage, allowing for precise positioning and isolation of target analytes through controlled movement and vibration, enabling accurate detection and isolation of biological materials on various substrates.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a picker system is used to isolate target analytes from substrates, then the ability to process biological samples is improved, but the accuracy and efficiency of substrate surface detection deteriorates

Engineering Contradiction:
Improveability to process biological samplesVSAvoidsubstrate surface detection accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent introduces an optical detector as an intermediary component that indirectly detects substrate surfaces through light interaction. The detector uses light sources and sensors to measure substrate position and characteristics without mechanical contact, resolving the conflict between mechanical picking operations and detection accuracy by separating the detection function from the picking mechanism.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces mechanical detection methods with optical detection systems. Instead of using mechanical sensors that physically contact the substrate, the system employs optical fields (light sources and detectors) to sense substrate position and properties, eliminating mechanical interference and improving measurement precision while maintaining productivity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If substrate detection systems are made more complex to improve detection accuracy, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvesubstrate surface detection accuracyVSAvoiddetection system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent implements a multi-functional optical detection system where a single integrated detector assembly performs multiple functions: substrate position detection, surface characteristic analysis, and coordination with the picker system. This universal detector reduces overall system complexity by consolidating multiple specialized components into one versatile unit that handles various detection tasks.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS11054346B2Detecting a substrate
Publication Date: 2021.07.06 RARECYTE INC
  • US11054346B2 patent drawing
  • US11054346B2 patent drawing
  • US11054346B2 patent drawing

AI summary

This disclosure is directed to a system and method for detecting a surface of a substrate within a scanner.