Scleral Shield Light Therapy for Meibomian Gland Dysfunction

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Solution Overview

Problem

Current methods for diagnosing and treating meibomian gland dysfunction (MGD) and blepharitis are limited, as they are often cumbersome for clinicians and painful for patients, with existing treatments like hot compresses and intense pulsed light being inefficient and expensive, and antibiotics can cause side effects.

Innovation Solution

A device and method using a scleral shield and energy transducer to apply targeted light energy to heat the eyelid and meibomian glands, with adjustable wavelengths to soften meibum and reduce bacterial load, while allowing visualization of the eyelid and gland ducts for optimized treatment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Difficulty of detecting and measuring

If transillumination techniques are used to examine meibomian glands, then gland visualization is improved, but patient comfort deteriorates due to requiring lid eversion

Engineering Contradiction:
Improvegland visualizationVSAvoidpatient comfort
Core Design Contradiction:
Difficulty of detecting and measuringVSEase of operation

Solution Approach 1:

Instead of requiring the patient to evert their lid for examination, the device allows the clinician to view the glands through the closed lid using transillumination. The light source is positioned to illuminate the glands from the outer lid surface, and the camera captures images through the closed lid, effectively inverting the traditional examination approach and eliminating patient discomfort.

Inventive Principle:
Principle #13The other way round (Inversion)

Solution Approach 2:

The device introduces an intermediary system consisting of a light source, camera, and image processing components that enable non-contact visualization of the glands through the closed lid. This intermediary system allows the clinician to examine glands without direct manipulation of the lid, maintaining patient comfort while achieving detailed visualization.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If conventional treatments like hot compresses are used, then treatment simplicity is improved, but treatment efficacy deteriorates

Engineering Contradiction:
Improvetreatment simplicityVSAvoidtreatment efficacy
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The device replaces conventional mechanical hot compresses with a light-based photothermal treatment system. A light source delivers specific wavelengths of energy that are absorbed by the meibomian glands, generating heat locally to melt blocked meibum. This substitution provides more precise and effective treatment while maintaining ease of application through automated delivery.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The device changes the treatment parameter from general heat application (hot compresses) to specific wavelength light energy delivery. By selecting specific wavelengths that are absorbed by meibomian gland tissue, the system achieves targeted thermal effects that are more effective at unclogging glands while controlling temperature to avoid tissue damage.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If intense pulsed light treatment is used, then treatment effectiveness is improved, but device complexity and cost increase

Engineering Contradiction:
Improvetreatment effectivenessVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The device segments the light delivery system into distinct functional components: a light source module, a wavelength selection system, and a camera imaging system. This segmentation allows each component to be optimized independently and simplifies the overall system architecture compared to conventional intense pulsed light devices, reducing complexity while maintaining effectiveness.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively softens meibum, reduces bacterial load, and provides a more comfortable and controlled treatment process, improving the efficacy of meibomian gland treatment and reducing patient discomfort.

Implementation Method 1

light energy from the energy transducer passes through the eyelid and heats the energy-absorbing surface

Methodology Applied
Scientific EffectLight absorption: Absorption (EM radiation)

Implementation Method 2

Tissue adjacent to the energy-absorbing surface is then warmed by conductive heating

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Implementation Method 3

The energy transducer is further configured to provide light energy at a second wavelength selected to be absorbed by the eyelid tissue, and thereby heat the eyelid tissue

Methodology Applied
Scientific EffectLight absorption: Absorption (EM radiation)

Implementation Method 4

The energy transducer is further configured to provide light energy at a third wavelength selected to treat bacteria

Methodology Applied
Scientific EffectLight absorption: Absorption (EM radiation)

Data Source

PatentUS11065152B2Systems and methods for the treatment of eye conditions
Publication Date: 2021.07.20 ALCON INC
  • US11065152B2 patent drawing
  • US11065152B2 patent drawing
  • US11065152B2 patent drawing

AI summary

Systems, methods, and devices used to treat eyelids, meibomian glands, ducts, and surrounding tissue are described herein. In some embodiments, an eye treatment device is disclosed, which includes a scleral shield positionable proximate an inner surface of an eyelid, the scleral shield being made of, or coated with, an energy-absorbing material activated by a light energy, and an energy transducer positionable outside of the eyelid, the energy transducer configured to provide light energy at one or more wavelengths, including a first wavelength selected to heat the energy-absorbing material.