Succinate Dehydrogenase Inhibitor Potentiator Compositions

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Solution Overview

Problem

Succinate dehydrogenase inhibitors, such as carboxamides, are effective but costly and require high doses for satisfactory results, limiting their use due to high costs and inefficacy at lower doses.

Innovation Solution

Combining succinate dehydrogenase inhibitors with potentiators, which are inexpensive and exhibit little antimicrobial activity, to enhance the inhibitors' efficacy, allowing for reduced inhibitor concentrations while maintaining effectiveness.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If succinate dehydrogenase inhibitors are used at high doses to achieve satisfactory results, then the effectiveness against microbes is improved, but the cost increases and affordability decreases

Engineering Contradiction:
Improveeffectiveness against microbesVSAvoidcost
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent combines succinate dehydrogenase inhibitors with potentiators to create a composite composition. The potentiator enhances the activity of the inhibitor, allowing lower doses of the expensive inhibitor to achieve the same level of microbial control effectiveness, thereby reducing overall cost while maintaining reliability

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent changes the concentration parameter of the succinate dehydrogenase inhibitor from high doses to lower doses by introducing a potentiator. This parameter change is enabled by the potentiator's ability to enhance the inhibitor's activity, allowing the system to achieve the same effectiveness at lower inhibitor concentrations

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If succinate dehydrogenase inhibitors are used at low doses to reduce cost, then the affordability improves, but the effectiveness against microbes becomes unsatisfactory

Engineering Contradiction:
ImprovecostVSAvoideffectiveness against microbes
Core Design Contradiction:
Quantity of substanceVSReliability

Solution Approach 1:

The potentiator acts as an intermediary substance that enhances the activity of the succinate dehydrogenase inhibitor. By introducing this mediator, the system can achieve satisfactory microbial control effectiveness at lower inhibitor doses, making the treatment more affordable while maintaining reliability

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent modifies the concentration parameter of the inhibitor by introducing a potentiator that amplifies its activity. This allows the system to operate at lower inhibitor concentrations while maintaining the same level of effectiveness, thereby reducing cost without sacrificing reliability

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS10829648B2Succinate dehydrogenase inhibitor containing compositions
Publication Date: 2020.11.10 ARCH WOOD PROTECTION INC

AI summary

A composition containing succinate dehydrogenase inhibitor and a potentiator has been discovered to enhance the activity of the succinate dehydrogenase such that the amount of the succinate dehydrogenase inhibitor need to effectively treat a microbial substance can be reduced substantially. The compositions may be used as additives for paints and coatings, and protecting crops, seeds, wallboard, metal working fluids, wood from mold, fungi and other microbes.