Sealed Unit Dose for Periodontitis with Inert Atmosphere
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Solution Overview
Problem
Conventional treatments for periodontosis, particularly those involving sodium bicarbonate and sodium percarbonate, face challenges in maintaining stability over time due to environmental factors, leading to reduced effectiveness and compliance issues for patients.
Innovation Solution
A single-use unit dose of dry powder mixture comprising sodium bicarbonate and sodium percarbonate, stored in a sealed packaging under an inert atmosphere, ensures stability and ease of use by eliminating the need for measurement and providing a consistent active formulation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Stability of the object's composition
If sodium bicarbonate and sodium percarbonate are stored in open packaging, then the mixture is accessible and easy to use, but the mixture loses stability and effectiveness over time
Solution Approach 1:
The patent applies an inert atmosphere (nitrogen or carbon dioxide) inside the sealed packaging to prevent moisture and oxygen from degrading the sodium percarbonate and sodium bicarbonate mixture. This maintains the mixture's stability and hydrogen peroxide release capability while allowing easy access when the package is opened for use.
Solution Approach 2:
The patent uses a sealed packaging with a flexible barrier layer (such as foil or laminated film) to protect the mixture from environmental moisture and oxygen. This flexible barrier maintains the mixture's stability while allowing the package to be easily handled and opened by patients.
2Reliability
If the packaging is sealed to maintain stability, then the mixture remains effective, but the device complexity increases
Solution Approach 1:
The patent introduces an inert atmosphere (nitrogen or carbon dioxide) into the sealed packaging to prevent degradation of the sodium percarbonate and sodium bicarbonate. This simple gas-filled barrier maintains effectiveness without requiring complex active preservation systems.
Solution Approach 2:
The patent divides the treatment into single-use unit doses, each in its own sealed packaging. This segmentation allows simple, effective packaging for each individual use without requiring complex multi-component systems or long-term stabilization mechanisms.
3Ease of operation
If the patient prepares the paste daily, then the treatment can be customized, but the compliance and ease of operation deteriorates
Solution Approach 1:
The patent pre-mixes the sodium bicarbonate and sodium percarbonate in the correct proportions during manufacturing and seals the mixture in single-use packaging. This preliminary action eliminates the need for patients to measure and mix components daily, significantly improving compliance and ease of use while maintaining treatment effectiveness.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The sealed packaging with an inert atmosphere maintains the mixture's stability and activity, ensuring effective hydrogen peroxide release for bacterial elimination, enhancing treatment compliance and efficacy.
Implementation Method 1
sodium percarbonate to release hydrogen peroxide upon application of the composition to the mouth
Implementation Method 2
Hydrogen peroxide, which degrades in the presence of protonated or cationic species in the presence of water in the mouth to give water and oxygen in gaseous form, allows the elimination of Gram-negative and anaerobic bacteria
Implementation Method 3
The abrasive aspect of the sodium bicarbonate particles in the paste applied by brushing makes it possible to mechanically break the biofilm and release the bacterial colonies
Implementation Method 4
Hydrogen peroxide, which degrades in the presence of protonated or cationic species in the presence of water in the mouth to give water and oxygen in gaseous form
Data Source
Figure 1~2
AI summary
The invention relates to a disposable unit dose for the treatment of periodontosis, containing a dry powder mixture, wherein the dry powder mixture comprises sodium bicarbonate and sodium percarbonate, and the unit dose is in the form of a sealed packaging containing the dry powder mixture, in which said mixture is stored in an inert atmosphere.