Sealing Member Metering for Ophthalmic Drop Sterility

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing dispensing devices for ophthalmic liquids face contamination risks due to liquid penetration into undesired zones, particularly because metering means are often separate from the sealing member, leading to potential bacterial growth and increased 'dead volume' that can harbor contaminants.

Innovation Solution

Incorporating metering means directly into the sealing member, which can take up a liquid release and non-return position, reduces contamination risks by minimizing 'dead volume' and ensuring the liquid is received directly by the metering means without flowing through other parts, thereby maintaining sterility.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If metering means are provided on a part other than the sealing member (e.g., outer casing), then the device structure is more flexible, but liquid can penetrate into other parts of the device causing contamination

Engineering Contradiction:
Improvesterility of dispensed liquidVSAvoiddevice structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges the metering means directly into the sealing member, eliminating the need for separate metering components in the outer casing. This integration ensures that liquid is metered immediately upon release from the sealed zone, preventing penetration into other device parts and eliminating contamination risks while maintaining structural simplicity

Inventive Principle:
Principle #5Merging (Combining)

2Reliability

If metering means are separate from the sealing member, then the device is easier to manufacture, but dead volume increases leading to contamination risks

Engineering Contradiction:
Improvesterility of dispensed liquidVSAvoiddead volume
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

By integrating metering means into the sealing member, the patent eliminates the space between these components, thereby minimizing dead volume. The sealing member's movement directly controls liquid release and metering in one continuous action, preventing contaminated liquid accumulation and reducing substance loss

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If the sealing member is made of flexible material, then it can fit snugly to reduce dead volume, but the material selection becomes more constrained

Engineering Contradiction:
Improvesterility of dispensed liquidVSAvoidmaterial selection
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent employs a flexible sealing member made of elastomeric material that can deform to fit snugly against the device interior surfaces. This flexibility enables the sealing member to minimize dead volume by conforming to the device geometry while maintaining effective sealing, and the elastomeric material is selected for its compatibility with liquid dispensing applications

Inventive Principle:
Principle #30Flexible shells and thin films

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This configuration enhances the sterility of dispensed liquid by reducing contamination risks and minimizing 'dead volume', ensuring that the metering process occurs closer to the sealed zone, thus preventing bacterial growth and maintaining the integrity of the dispensed drops.

Implementation Method 1

The device includes bearing means for bearing against the sealing member, in register with a recessed zone, serving to deform the sealing member by bending deformation so that it takes up its non-return position

Methodology Applied
Scientific EffectBending deformation: Deformation

Implementation Method 2

the device includes bearing means for bearing against the sealing member, serving to deform the flexible portion of the sealing member by compression deformation so that it takes up its non-return position

Methodology Applied
Scientific EffectCompression deformation: Compression

Implementation Method 3

The device includes a liquid-passing channel opening out into the drop-forming means and the drop-forming means comprise a flared shape that flares from said channel. This flared shape makes it possible to avoid jets of liquid being sprayed out

Methodology Applied
Scientific EffectFluid flow redirection:

Data Source

PatentUS11524822B2Device for dispensing a liquid in the form of drops
Publication Date: 2022.12.13 NEMERA LA VERPILLIERE SAS
  • US11524822B2 patent drawing
  • US11524822B2 patent drawing

AI summary

The device makes it possible to dispense predetermined metered quantities of liquid. It includes a sealing member that can take up a liquid release position, allowing liquid to flow out of the device, and a non-return position preventing liquid from flowing back into the device. The sealing member is provided with metering means for metering out the liquid to be dispensed.