Sealing Valve Outlet Structure to Prevent Nozzle Crystallization

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing liquid outlet structures for reagent kits are cumbersome and time-consuming to operate, requiring frequent tip changes or cleaning of pipettes and syringes, and are not conducive to automation due to operator-dependent reagent dispensing.

Innovation Solution

A sealing valve with a cylindrical valve hole and frustum hole, integrated with a spray pipe and nozzle, uses a magnet bar to control the opening and closing of the nozzle, ensuring good sealing and preventing liquid crystallization, while allowing for easy automation and miniaturization.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a traditional pipette or syringe is used to draw reagents, then the reagent can be transferred, but the operation is cumbersome and time-consuming requiring frequent tip changes or cleaning

Engineering Contradiction:
Improvereagent dispensing efficiencyVSAvoidoperation complexity
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The sealing valve integrates the drawing, sealing, and dispensing functions into a single component. The valve body with valve hole and frustum hole combines the liquid passage and sealing mechanism, eliminating the need for separate pipette tips or syringe components that require frequent changing or cleaning.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The magnet bar automatically seals the valve hole when not in use, and the frustum hole automatically retains liquid through capillary action. This self-sealing and self-retaining mechanism eliminates the need for manual cap replacement or cleaning operations.

Inventive Principle:
Principle #25Self-service

2Productivity

If the nozzle is exposed to air, then liquid can be dispensed, but the liquid rapidly evaporates and crystallizes blocking the nozzle

Engineering Contradiction:
Improveliquid dispensing capabilityVSAvoidnozzle blockage prevention
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The magnet bar proactively seals the valve hole before liquid evaporation can occur. The frustum hole design with capillary retention prevents liquid from reaching the nozzle when not in use, acting in advance to prevent crystallization and blockage.

Inventive Principle:
Principle #9Preliminary anti-action

Solution Approach 2:

The frustum hole acts as an intermediary chamber between the liquid storage and nozzle. It uses capillary forces to retain liquid and prevent it from contacting the nozzle when not dispensing, while still allowing smooth flow when needed.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Extent of automation

If the liquid outlet structure is simplified for automation, then automation becomes easier, but sealing performance may deteriorate

Engineering Contradiction:
Improveautomation compatibilityVSAvoidsealing performance
Core Design Contradiction:
Extent of automationVSReliability

Solution Approach 1:

The patent replaces manual mechanical operations (cap replacement, syringe cleaning) with a magnetic field-controlled system. The magnet bar responds to magnetic field changes to automatically open or close the valve, enabling integration with automated liquid handling systems while maintaining reliable sealing.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The sealing mechanism uses changes in magnetic field parameters to control the magnet bar position. When the magnetic field strength changes, the magnet bar moves to seal or open the valve hole, providing automated control without compromising sealing reliability.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The sealing valve effectively controls the liquid outlet, preventing air leakage and liquid crystallization, while facilitating easy disassembly and automation, enhancing operational efficiency and precision in reagent dispensing.

Implementation Method 1

a magnet bar provided in the spray hole... The magnet bar moves along an axial direction of the spray hole

Methodology Applied
Scientific EffectMagnetic force: Magnetism

Implementation Method 2

can store a portion of liquid that is used for soaking the conical nozzle opening and preventing the liquid inside the nozzle from rapidly evaporating and crystallizing

Methodology Applied
Scientific EffectEvaporation prevention: Evaporation

Implementation Method 3

a conical nozzle opening provided at an end portion of the nozzle pipe such to prevent liquid from adhering to a lower end of the nozzle

Methodology Applied
Scientific EffectConical geometry effect: Geometry

Data Source

PatentEP4246021B1Liquid outlet structure comprising a sealing valve
Publication Date: 2025.06.18 SHIJIAZHUANG HIPRO BIOTECH
  • EP4246021B1 patent drawingFigure 1
  • EP4246021B1 patent drawingFigure 2~3
  • EP4246021B1 patent drawingFigure 4

AI summary

A sealing valve comprises a sealing valve body (1). The sealing valve body (1) is provided with a cylindrical valve hole (2), and a bottom end of the cylindrical valve hole (2) is provided with a frustum hole (3). The frustum hole (3) is arranged coaxially with the cylindrical valve hole (2), and a small bottom end of the frustum hole (3) is in communication with the bottom end of the cylindrical valve hole (2). The sealing valve is controllable over the opening and closing of a nozzle and can prevent crystallization of a liquid at the nozzle.