Seawater Nanoparticle Formulations for Nutrient Bioavailability

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Solution Overview

Problem

Current formulations of vitamins, trace elements, and enzymes have limitations such as high concentrations leading to excessive doses, requiring multiple products for comprehensive nutrition, which can be costly, environmentally impactful, and reduce consumer compliance due to complexity and quality of life issues.

Innovation Solution

A composition comprising seawater, minerals, trace elements, vitamins, prebiotics, probiotics, enzymes, and oils, formulated into nanoparticles through homogenization and sonicating, creating liposomes or vesicles for enhanced bioavailability and controlled release, allowing for a balanced and sustained delivery of nutrients.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If current formulations of vitamins, trace elements, and enzymes are used, then comprehensive nutrition can be provided, but the complexity of requiring multiple products reduces consumer compliance and increases cost

Engineering Contradiction:
Improvecomprehensive nutrition coverageVSAvoidnumber of products required
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent combines multiple nutritional components (vitamins, trace elements, enzymes, probiotics, prebiotics) into a single integrated nanoparticle formulation. This merging of previously separate supplements into one product resolves the contradiction by maintaining comprehensive nutrition coverage while eliminating the complexity of managing multiple products, thereby improving consumer compliance

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The nanoparticle composition serves multiple nutritional functions simultaneously - providing vitamins, minerals, enzymes, probiotics, and prebiotics in a single formulation. This multi-functionality allows one product to replace multiple specialized supplements, resolving the contradiction between comprehensive nutrition and product complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Quantity of substance

If high concentrations of nutrients are used in formulations, then nutritional needs can be met, but excessive doses may cause harmful effects

Engineering Contradiction:
Improvenutrient concentrationVSAvoidexcessive dose effects
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The nanoparticle formulation enables dynamic, controlled release of nutritional components over time. Instead of delivering all nutrients at once in high concentrations, the system releases them progressively, maintaining safe concentration levels while still meeting total nutritional requirements, thus resolving the contradiction between adequate nutrition and avoiding excessive doses

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The formulation employs periodic release of nutritional components through the nanoparticle degradation and dissolution process. Nutrients are delivered in controlled intervals rather than as a single high-concentration bolus, preventing harmful peak concentrations while ensuring adequate total delivery over time

Inventive Principle:
Principle #19Periodic action

3Adaptability or versatility

If multiple separate supplements are used to provide comprehensive nutrition, then all nutritional needs can be addressed, but the cost and environmental impact increase

Engineering Contradiction:
Improvenutritional completenessVSAvoidenvironmental impact
Core Design Contradiction:
Adaptability or versatilityVSLoss of substance

Solution Approach 1:

By merging multiple nutritional supplements into a single nanoparticle formulation, the patent reduces the total packaging material, manufacturing resources, and transportation requirements. This consolidation maintains nutritional completeness while significantly reducing environmental impact through decreased waste and resource consumption

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition provides reproducible manufacturing, protects sensitive ingredients, ensures controlled immediate and sustained release, improves bioavailability, and simplifies nutritional intake by offering a single product for multiple nutritional needs, reducing environmental impact and enhancing consumer compliance.

Implementation Method 1

comprising homogenizing, and/or sonicating a seawater and oil composition, leading to liposomes or vesicles of nanoparticle size

Methodology Applied
Scientific EffectHomogenization:

Implementation Method 2

comprising homogenizing, and/or sonicating a seawater and oil composition, leading to liposomes or vesicles of nanoparticle size

Methodology Applied
Scientific EffectSonication: Ultrasonic Vibration

Implementation Method 3

leading to liposomes or vesicles of nanoparticle size

Methodology Applied
Scientific EffectLiposome formation: Amphiphiles

Implementation Method 4

creating liposomes or vesicles for enhanced bioavailability and controlled release

Methodology Applied
Scientific EffectEncapsulation:

Data Source

PatentEP3441062B1Seawater and salt powder balancing formulations and nutritional and pharmaceutical compositions
Publication Date: 2023.11.29 SALAMA MAGDY
  • EP3441062B1 patent drawingFigure 1

AI summary

The invention relates to a composition, comprising at least one of seawater, crystalline and/or amorphous seawater salt and/or seawater salt powder, and one or more minerals, trace elements, vitamins, prebiotics, probiotics, enzymes, co-enzymes, parts of a plant and/or plant extracts, preferably parts of a fruit or vegetable or fruit or vegetable extracts, and one or more oils, wherein said composition is obtained using a particle method, preferably a method comprising vortexing, agitating, homogenizing, and/or sonicating a seawater and oil composition, leading to liposomes, vesicles, and/or nanodroplets of nano- and/or microparticle size, or mixtures thereof.