Seed Coating with Gallates for Heat-Sensitized Pathogen Control

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Solution Overview

Problem

Current seed protection methods are inadequate in addressing oxidative stress and pathogen contamination, particularly due to the development of resistance to thermal treatments, and often rely on toxic chemicals that can harm crops and the environment.

Innovation Solution

Coating seeds with an antioxidant and antimicrobial composition containing C7-18 gallates, followed by a controlled heat treatment between 20° C. to 70° C. for 5 to 60 minutes, to enhance seed protection against oxidants and microorganisms without compromising crop quality or safety.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If high heat treatment (e.g., 70°C) is applied to prevent fungal contamination, then pathogen control is improved, but seed quality and viability deteriorate

Engineering Contradiction:
Improvepathogen controlVSAvoidseed quality
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent applies preliminary action by coating seeds with C7-18 gallates before heat treatment. This pre-coating creates a protective layer that sensitizes pathogens to heat while protecting seed tissues, enabling effective pathogen control at lower temperatures that preserve seed quality and viability.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

C7-18 gallates serve as an intermediary substance that mediates between heat treatment and seed pathogens. The gallates accumulate in pathogen cells and sensitize them to heat, allowing pathogen control at lower temperatures that do not damage seed quality, thus resolving the contradiction between effective sterilization and seed preservation.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If intensive heat treatment is applied to kill pathogens, then microbial contamination is reduced, but seed integrity and fertility are compromised

Engineering Contradiction:
Improvemicrobial contaminationVSAvoidseed integrity
Core Design Contradiction:
Object-affected harmful factorsVSStrength

Solution Approach 1:

The patent changes the temperature parameter from conventional high heat (70°C) to mild heat (20-70°C) by combining it with C7-18 gallate treatment. The gallates enable pathogen death at lower temperatures through heat sensitization, preserving seed integrity and fertility while still achieving effective microbial control.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If conventional biocides are used to protect seeds from pathogens, then disease control is improved, but resistance development and environmental harm occur

Engineering Contradiction:
Improvedisease controlVSAvoidresistance and toxicity
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent changes from chemical biocide application to a physical heat treatment approach enabled by C7-18 gallate sensitization. This parameter change from chemical to physical control method avoids resistance development and environmental toxicity while maintaining effective disease control through mild heat treatment.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method effectively inhibits microbial growth and oxidative damage, offering a sustainable and cost-effective alternative to conventional seed treatments by leveraging the heat-sensitizing properties of long-chain alkyl gallates, thereby improving seed viability and crop safety.

Implementation Method 1

We found a new utility for long-chain alkyl gallates as heat-sensitizing agents which enables high-efficiency pathogen intervention under decreased temperatures

Methodology Applied
Scientific EffectHeat sensitization:

Implementation Method 2

ROS accumulation during seed desiccation or aging is an example of abiotic stress where the seed damage by ROS results in the degradation/deterioration of cellular components

Methodology Applied
Scientific EffectOxidation: Oxidation

Implementation Method 3

subsequently heating the seeds to a temperature of about 20° C. to about 70° C. for about 5 minutes to about 60 minutes prior to planting the seeds

Methodology Applied
Scientific EffectThermal treatment: Heat Treatment

Data Source

PatentUS11950596B2Methods of protecting seeds from oxidants and microorganisms
Publication Date: 2024.04.09 THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
  • US11950596B2 patent drawing
  • US11950596B2 patent drawing
  • US11950596B2 patent drawing

AI summary

Disclosed are methods of protecting seeds from oxidants and microorganisms prior to planting said seed, involving coating the seeds with an antioxidant effective amount and an antimicrobial effective amount of a composition containing at least one compound selected from the group consisting of C7-18 gallates in an optional solvent and/or optional carrier prior to planting the seeds, and heating the seeds to a temperature of about 20° C. to about 70° C. for about 5 minutes to about 60 minutes prior to planting the seeds.