Segmented Bioprocessing Vessel for Wrinkle-Free Cylindrical Deployment

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Solution Overview

Problem

Existing flexible bioprocessing vessels face challenges in efficient manufacturing, shipping, and deployment within cylindrical rigid support structures due to their large size, limited hoist points, and potential wrinkling, which can create non-uniform fluid zones and require user manipulation.

Innovation Solution

A flexible bioprocessing vessel design featuring at least six side panels, a top panel, and a bottom panel, with vertical welds and circumferential hoisting points, allowing for easy installation and minimizing wrinkling, and is configured to fit closely within cylindrical support structures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If flexible bags are made relatively large (2000L-3000L capacity) for use within rigid support structures, then the processing capacity is improved, but the bags become challenging to ship, install and deploy

Engineering Contradiction:
Improveprocessing capacityVSAvoidshipping and deployment ease
Core Design Contradiction:
Quantity of substanceVSEase of operation

Solution Approach 1:

The flexible bag is divided into multiple panels (at least four panels) that are joined together. This segmentation allows the large-capacity bag to be manufactured in manageable sections that can be more easily shipped and deployed while maintaining the required processing capacity when assembled.

Inventive Principle:
Principle #1Segmentation

2Device complexity

If flexible bags include relatively few hoist points (2-4 points) to simplify the structure, then the device complexity is reduced, but the possibility of wrinkling during deployment increases

Engineering Contradiction:
Improvenumber of hoist pointsVSAvoiddeployment uniformity
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

Hoist points are strategically positioned at specific locations on the flexible bag, particularly near the top edges of panels. This localized placement of hoist points at critical areas provides better control during deployment, reduces wrinkling, and ensures uniform raising of the bag without requiring an excessive number of hoist points throughout the entire structure.

Inventive Principle:
Principle #3Local quality

3Ease of manufacture

If flexible bags are manufactured from a relatively small number of panels (e.g., four panels) to simplify manufacturing, then the manufacturing process is simplified, but the bags are generally oversized and do not conform closely to cylindrical interior

Engineering Contradiction:
Improvemanufacturing simplicityVSAvoidcylindrical conformance
Core Design Contradiction:
Ease of manufactureVSShape

Solution Approach 1:

The flexible bag is designed with curved surfaces and panels that are shaped to conform to the cylindrical interior of rigid support structures. By incorporating curvature into the panel designs and their arrangements, the bag achieves better cylindrical conformance while maintaining a manageable number of panels for manufacturing.

Inventive Principle:
Principle #14Spheroidality (Curvature)

4Ease of operation

If flexible bags are dimensionally larger than necessary to accommodate maximum fill levels, then the manufacturing and deployment is easier, but the headspace is not uniform in curvature or size

Engineering Contradiction:
Improvedeployment easeVSAvoidheadspace uniformity
Core Design Contradiction:
Ease of operationVSShape

Solution Approach 1:

The dimensions and curvature parameters of the flexible bag panels are optimized to achieve uniform headspace when the bag is filled to its maximum capacity. By carefully adjusting these geometric parameters, the design ensures that the bag maintains uniform curvature and headspace characteristics while remaining easy to deploy within cylindrical support structures.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20250340809A1Flexible bioprocessing vessel
Publication Date: 2025.11.06 GLOBAL LIFE SCIENCES SOLUTIONS USA LLC
  • US20250340809A1 patent drawing
  • US20250340809A1 patent drawing
  • US20250340809A1 patent drawing

AI summary

A flexible bioprocessing vessel includes at least six side panels forming sides of the flexible bioprocessing vessel, a top panel adjoining the at least six side panels, the top panel forming a top of the flexible bioprocessing vessel, a bottom panel adjoining the at least six side panels, the bottom panel forming a bottom of the flexible bioprocessing vessel, the at least six side panels, top panel, and bottom panel defining an interior cavity configured for processing a fluid, the at least six side panels joined together via vertical welds. The vessel further includes at least one fluid input and at least one fluid output for adding and removing fluid to and from the interior cavity respectively. Wherein the flexible bioprocessing vessel is configured for use within a rigid support structure having a cylindrical interior.