Segmented Pneumatic Cuff for Arterio-Venous Gradient Control

The device divides the compression function into two independent inflatable bladders: a first bladder for compressing the thigh and a second bladder for compressing the leg. This segmentation allows independent control of compression in different anatomical regions, enabling optimized venous drainage from the thigh while simultaneously improving arterial perfusion to the lower leg and foot through targeted compression sequences.

The device implements periodic compression cycles with specific timing: the first bladder compresses the thigh for 20 seconds followed by 40 seconds of decompression, while the second bladder compresses the leg for 40 seconds followed by 20 seconds of decompression. This periodic action creates rhythmic pressure gradients that enhance both venous return and arterial inflow at different phases of the cycle, addressing both venous drainage and arterial perfusion requirements.

The device dynamically adjusts compression timing and sequence for different bladders rather than applying uniform static compression. The thigh compression (first bladder) and leg compression (second bladder) operate with different durations and timing within the same cycle, creating dynamic pressure gradients that favor venous drainage during compression phases while allowing arterial reperfusion during decompression phases. This dynamic approach prevents sustained high pressure that would compromise arterial flow.

The device applies preliminary compression to the thigh (first bladder) before full leg compression (second bladder) in the treatment sequence. This preliminary action on the proximal segment creates initial pressure gradients that facilitate venous drainage from the upper limb, preparing the system for subsequent distal compression while maintaining arterial perfusion pressure through the controlled sequencing of compression events.