Segmented Thrombectomy Mesh for Radial Force Control
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Solution Overview
Problem
Existing medical devices for extracting thrombus from blood vessels often result in thrombus fragmentation and dispersion due to inadequate radial force distribution and adaptation to vessel geometry, leading to incomplete removal and potential vessel damage.
Innovation Solution
A self-expandable device with a mesh of intertwined helicoidal filaments, featuring varying braiding angles and closed loops, which provides higher radial forces for apposition against the vessel wall, facilitating thrombus capture and aspiration while minimizing vessel damage and flow disruption.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Force
If a conventional extraction device is used, then the device structure is simple, but the device cannot provide sufficient radial force for apposition against the vessel wall, resulting in thrombus fragmentation
Solution Approach 1:
The device divides the mesh into multiple sections with different braiding angles. The first section has a first braiding angle optimized for radial force generation, while the second section has a second braiding angle for different functional requirements. This segmentation allows each section to contribute differently to the overall performance, with the first section providing the necessary radial force for vessel wall apposition without requiring the entire device structure to be complex.
Solution Approach 2:
Different sections of the mesh are assigned different local properties through varying braiding angles. The first section possesses higher radial stiffness due to its specific braiding angle, enabling it to provide concentrated radial force for apposition against the vessel wall where it is most needed for thrombus capture, while other sections have different properties suited for their specific functions.
2Adaptability or versatility
If the device expands uniformly, then the expansion is simple to control, but the device cannot adapt to varying vessel geometry, reducing thrombus capture effectiveness
Solution Approach 1:
The mesh is segmented into multiple sections, each with distinct braiding angles tailored to specific functional requirements. The first section has a braiding angle optimized for radial expansion and vessel wall apposition, while the second section has a different braiding angle for maintaining structural integrity or providing flexibility. This segmentation enables the device to adapt to varying vessel geometries through differential expansion characteristics of each section.
Solution Approach 2:
Each section of the mesh is赋予 different local expansion properties through its specific braiding angle. The first section's braiding angle is designed to provide greater radial compliance for adapting to vessel curvature and achieving apposition against the vessel wall, while the second section maintains different properties for its specific function, creating a device with spatially varying adaptability.
3Force
If the mesh has uniform structure, then the manufacturing is simple, but the device cannot provide differentiated radial forces along its length, reducing thrombus retention
Solution Approach 1:
The mesh is manufactured as distinct sections with different braiding angles. The first section is constructed with a first braiding angle to provide specific radial force characteristics for vessel wall apposition, while the second section is constructed with a second braiding angle for different functional requirements. This segmentation approach to manufacturing allows for controlled variation in radial force distribution along the device length while maintaining manufacturing feasibility through modular construction.
4Strength
If the device uses a single braiding angle, then the structure is uniform and simple, but the device cannot optimize both radial force and flexibility simultaneously
Solution Approach 1:
The device divides the mesh into a first section with a first braiding angle optimized for radial strength and vessel wall apposition, and a second section with a second braiding angle optimized for other properties such as flexibility or structural support. This segmentation allows the first section to provide the necessary radial strength where needed without requiring the entire device to have a complex multi-angle braid pattern.
Solution Approach 2:
The first section of the mesh is assigned a specific braiding angle that provides higher radial strength for effective vessel wall apposition and thrombus capture, while the second section has a different braiding angle suited for its specific function. This local differentiation of braiding angles allows optimization of radial strength in the critical first section without making the entire device structure overly complex.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device effectively captures and removes thrombi with reduced risk of fragmentation and vessel injury, ensuring complete thrombus retrieval and improved navigability within blood vessels.
Implementation Method 1
a self-expandable device with a mesh of intertwined helicoidal filaments... which provides higher radial forces for apposition against the vessel wall
Implementation Method 2
provides higher radial forces for apposition against the vessel wall, facilitating thrombus capture and aspiration
Data Source
AI summary
A device, a thrombectomy apparatus and a method for extraction of thrombus from a blood vessel are disclosed. The device comprises a segment changing its shape from a retracted position in a compressed state to an extended and expanded position. The segment is formed by a mesh of at least two sets of helicoidal filaments turning respectively in opposite directions and being intertwined. The mesh comprises two distinct tubular sections. The mesh of the first section has helicoidal filaments with a braiding angle providing radial forces higher than in the second section, thus the first section becomes appositioned against the inner wall of the blood vessel. The second section comprises two sub-sections. The first sub-section has a conical shape and comprises a braiding angle changing at its proximal and distal ends to provide radial strength to maintain the conical shape and to stop a proximal blood flow during the removal of the thrombus.