Seizure Detection via Inverse Compression Ratio

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current seizure detection methods are labor-intensive, subjective, and lack real-time automated processing capabilities, making it difficult to effectively manage seizures, especially for patients with refractory epilepsy, and existing automated methods fail to achieve the performance of human specialists.

Innovation Solution

An automated seizure detection system using an EEG device, processor, and memory to calculate an inverse compression ratio based on EEG signals, triggering treatment when the ratio exceeds a classification threshold, employing lossless compression algorithms and capable of using implantable neurostimulators or drug pumps to stop seizure activity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual review of EEG signals by epileptologists is used, then measurement precision and reliability are improved, but productivity and time efficiency deteriorate

Engineering Contradiction:
Improveseizure detection accuracyVSAvoidprocessing speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent replaces manual mechanical review of EEG signals by epileptologists with an automated computational system. The system uses compression-based entropy estimation algorithms to automatically detect seizures in EEG data, substituting human expertise with automated processing that achieves comparable or superior detection accuracy while dramatically improving processing speed and throughput.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system performs self-service by automatically detecting seizures without requiring continuous human intervention. The automated algorithm continuously monitors EEG signals, identifies seizure patterns, and triggers appropriate responses independently, allowing the system to operate autonomously while maintaining high detection precision.

Inventive Principle:
Principle #25Self-service

2Productivity

If existing automated seizure detection methods are used, then productivity is improved, but measurement precision and reliability deteriorate

Engineering Contradiction:
Improveprocessing speedVSAvoiddetection accuracy
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent changes the fundamental parameter used for seizure detection from traditional spectral or temporal features to compression-based entropy estimation. By using the inverse compression ratio as a key indicator, the system achieves both high processing speed and reliable detection accuracy, overcoming the limitations of existing automated methods that prioritize speed at the expense of precision.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system incorporates feedback mechanisms where the compression-based entropy estimation continuously monitors EEG signals and adjusts detection thresholds based on real-time signal characteristics. This feedback loop enables the system to maintain high reliability in detection accuracy while preserving automated processing speed.

Inventive Principle:
Principle #23Feedback

3Measurement precision

If complex entropy calculation methods are used, then measurement precision is improved, but device complexity and computational requirements worsen

Engineering Contradiction:
Improvejoint entropy estimation accuracyVSAvoidcomputational complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts the essential information needed for seizure detection from complex EEG signals through compression-based entropy estimation. By using lossless compression algorithms, the system isolates the critical entropy characteristics that indicate seizure activity, separating these key features from the complexity of the raw EEG data without requiring computationally intensive processing.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system uses efficient, lightweight compression algorithms that can be quickly applied to EEG data without requiring complex computational resources. The inverse compression ratio calculation provides a simple yet effective metric for seizure detection that avoids the need for expensive or overly complex entropy calculation methods.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Data Source

PatentUS20230310857A1Systems and Methods for Seizure Detection Using Compression-Enabled Joint Entropy Estimation
Publication Date: 2023.10.05 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
  • US20230310857A1 patent drawing
  • US20230310857A1 patent drawing
  • US20230310857A1 patent drawing

AI summary

Systems and methods for seizure detection in accordance with embodiments of the invention are illustrated. One embodiment includes an automated seizure treatment system, including an electroencephalogram (EEG) device configured to record neural activity from a brain of a patient, a treatment device, a processor, and a memory, the memory containing a seizure detection application that configures the processor to obtain an EEG signal from the EEG device, calculate an inverse compression ratio based on the EEG signal, and when the inverse compression ratio is greater than a classification threshold, deliver treatment capable of stopping the seizure to the patient using the treatment device.