Selective UV Filter Composition for Inflammatory Skin Phototherapy
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Solution Overview
Problem
Existing dermatological treatments struggle to combine the protective effects of sunscreens with the therapeutic benefits of specific ultraviolet radiation exposure for inflammatory skin diseases, while minimizing side effects.
Innovation Solution
A composition that shields UVA radiation and allows UVB radiation in the 295 to 320 nm range to pass through, using a combination of diethylhexyl 2,6-naphthalate, diethylamino hydroxybenzoyl hexyl benzoate, and phenyl dibenzimidazole tetrasulfonate, to treat inflammatory skin diseases like psoriasis, atopic dermatitis, and rosacea.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If broad-spectrum UV shielding is applied to protect skin from damage, then skin protection from UVA and UVB radiation is improved, but therapeutic UVB radiation needed for treating inflammatory skin diseases is blocked
Solution Approach 1:
The patent segments the UV spectrum protection by using different shielding agents with specific wavelength selectivity. The composition blocks UVA radiation (320-400 nm) while creating a transmission window for therapeutic UVB radiation (295-320 nm), particularly around 311 nm for psoriasis treatment. This is achieved by carefully selecting and combining shielding agents that have absorption peaks in the UVA range but allow UVB passage.
Solution Approach 2:
The patent applies local quality by creating a wavelength-specific filtering effect at the skin surface. The shielding composition provides different levels of protection across the UV spectrum: high blocking for UVA, high transmission for therapeutic UVB (295-320 nm), and selective blocking for non-therapeutic UVB wavelengths. This spatially-uniform but spectrally-selective filtering enables simultaneous protection and therapy.
2Reliability
If UVB radiation is allowed to pass through for therapeutic benefit, then treatment of inflammatory skin diseases is improved, but skin damage from excessive UV exposure increases
Solution Approach 1:
The patent converts the potentially harmful effect of UVB radiation into a beneficial therapeutic effect by controlling the spectral composition. Instead of blocking all UVB radiation as conventional sunscreens do, the composition allows the specific therapeutic wavelength range (295-320 nm, particularly 311 nm) to pass through while blocking other UVB wavelengths that contribute to damage. This transforms UVB from a purely harmful agent into a controlled therapeutic tool.
Solution Approach 2:
The patent changes the spectral parameters of UV radiation reaching the skin by using shielding agents with specific absorption characteristics. The composition modifies the UV spectrum by selectively absorbing UVA and certain UVB wavelengths while transmitting the therapeutic window (295-320 nm). This parameter control is achieved by selecting shielding agents whose absorption spectra create the desired transmission profile, effectively tuning the radiation parameters for therapeutic benefit with minimized damage.
3Object-affected harmful factors
If conventional sunscreens are used to block all UV radiation, then skin protection is improved, but phototherapeutic treatment of skin diseases cannot be delivered
Solution Approach 1:
The patent achieves multi-functionality by creating a shielding composition that simultaneously provides sun protection and enables phototherapy. The same topical composition that protects the skin from harmful UVA and excessive UVB radiation also serves as a vehicle for delivering therapeutic UVB radiation. This dual functionality is accomplished by formulating the shielding agents to create a transmission window that aligns with the therapeutic wavelength requirements for treating inflammatory skin diseases like psoriasis and atopic dermatitis.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition provides broad-spectrum protection while allowing therapeutic UVB radiation to treat inflammatory skin diseases, reducing side effects and improving skin conditions.
Implementation Method 1
The shielding agents present in solar products, and which have the ability to interact with UV radiation, are also known as sun filters. These filters are divided into categories such as UVA filters, UVB filters and combined filters which partially overlap the protection in the UVA, UVB spectrums, depending on the ability to interact with ultraviolet radiation of a given wavelength.
Implementation Method 2
The shielding effect of solar products can be almost total or partial depending on the composition, the amounts of shielding agents present in the formulation, and the quantity applied to the skin.
Data Source
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AI summary
The present invention concerns a filtering composition for cutaneous application containing a combination of protective compounds which allow selected electromagnetic radiation with wavelengths from 295 to 320 nm to pass through. The ultraviolet radiation passed through the composition reaches the skin and stimulates specific biological responses suitable for the therapeutic and non- therapeutic cosmetic treatment of skin affections with an inflammatory component.