Selenium Sulfite Forage Additive Detoxifies Mycotoxins

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Solution Overview

Problem

Existing methods for detoxifying forage containing plants and plant parts are complex and limited in their ability to simultaneously metabolize and immobilize multiple harmful components like mycotoxins, particularly trichothecenes and zearalenones, as they often require specific substances or microorganisms that can only detoxify one or two mycotoxin families.

Innovation Solution

An additive comprising alkali or earth alkali metal sulfites and selenium-containing salts is used to detoxify trichothecenes and zearalenones, leveraging the germicidal effects of sulfites and the catalytic properties of selenium to efficiently convert mycotoxins into non-toxic metabolites, while also providing selenium as a micronutrient, and incorporating selenium yeast for enhanced detoxification and improved animal productivity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If specific substances or microorganisms are used to detoxify mycotoxins, then detoxification of specific mycotoxin families is achieved, but the ability to simultaneously detoxify multiple different mycotoxin families is limited

Engineering Contradiction:
Improveability to detoxify multiple mycotoxin familiesVSAvoidcomplexity of additive composition
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent applies universality by using a single additive composition containing selenium and sulfite that can detoxify multiple different mycotoxin families (trichothecenes, zearalenones, aflatoxins, ochratoxins) simultaneously, rather than requiring separate specialized substances for each mycotoxin type. This multi-functional approach resolves the contradiction by expanding adaptability while maintaining composition simplicity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent merges selenium-containing compounds and sulfite-containing compounds into a single additive composition that works synergistically to detoxify multiple mycotoxin families. This combination approach allows one additive to perform multiple detoxification functions, thereby improving versatility without proportionally increasing complexity.

Inventive Principle:
Principle #5Merging (Combining)

2Object-affected harmful factors

If combinations of mono-substituted amine compound and oxygen acid are used to metabolize mycotoxins, then detoxification is achieved, but the composition becomes relatively complex

Engineering Contradiction:
Improvemycotoxin detoxificationVSAvoidadditive composition complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent extracts and eliminates the need for complex combinations of mono-substituted amine compounds and oxygen acids by using a simpler composition based on selenium and sulfite. This extraction of unnecessary complexity while retaining effective detoxification function resolves the contradiction between achieving detoxification and maintaining composition simplicity.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs readily available, simple chemicals (selenium and sulfite compounds) that can be easily applied and work effectively without requiring complex stable formulations. This approach uses simple, easily obtainable substances to achieve the detoxification effect, reducing composition complexity while maintaining effectiveness.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Reliability

If individual detoxifying substances are used, then specific mycotoxins can be detoxified, but only one or two mycotoxin families can be addressed at a time

Engineering Contradiction:
Improvedetoxification effectivenessVSAvoidrange of mycotoxin families detoxified
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent applies universality by creating an additive composition that simultaneously targets multiple mycotoxin families (trichothecenes, zearalenones, aflatoxins, ochratoxins) with a single formulation. The selenium and sulfite components work together to provide broad-spectrum detoxification, thereby improving versatility while maintaining reliable detoxification effectiveness across different mycotoxin types.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent uses a composite material approach by combining selenium-containing compounds with sulfite-containing compounds in a single additive formulation. This composite composition leverages the synergistic effects of both components to achieve broad-spectrum mycotoxin detoxification, thereby expanding the range of detoxifiable mycotoxin families while maintaining effective and reliable performance.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The additive achieves efficient and complete detoxification of multiple mycotoxins, improving animal performance by ensuring the conversion of trichothecenes and zearalenones into non-toxic forms, providing essential selenium, and enhancing the overall productivity of farm animals.

Implementation Method 1

an alkali or earth alkali metal sulfite and/or a selenium-containing salt are included as an inorganic salt detoxifying trichothecene and/or zearalenone

Methodology Applied
Scientific EffectReduction: Reduction

Implementation Method 2

the use of only small quantities of alkali and/or earth alkali metal sulfites has particularly beneficial effects upon the disintegration of mycotoxins

Methodology Applied
Scientific EffectCatalysis: Catalysis

Implementation Method 3

the use of yeasts and/or yeast components, such as yeast cell walls, for example, with here mycotoxins being able to combine and/or adhere thereto and thus being rendered harmless

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentUS10575539B2Additive for selenium-containing forage
Publication Date: 2020.03.03 ERBER AG
  • US10575539B2 patent drawing
  • US10575539B2 patent drawing
  • US10575539B2 patent drawing

AI summary

An additive for selenium-containing forage, primarily comprising plants or plant parts, such as cereal, corn, grass, or alfalfa, including at least one salt detoxifying inorganic trichothecene and/or zearalenone, with an alkali or earth alkali metal sulfite and perhaps a selenium containing salt being included as the inorganic salt detoxifying trichothecene and/or zearalenone.