Selenium-Enriched Tea Polyphenol Selenide Coordination Complex
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Solution Overview
Problem
Current organic selenium health products have low selenium content due to toxicity limitations, hindering their full potential in disease prevention and health care applications.
Innovation Solution
Development of selenium-enriched tea polyphenol selenide with a selenium content of 23.4%, achieved through a method involving the reaction of tea polyphenol with inorganic metallic alkali and SeO2, forming a compound with an alkali metal ion and selenium coordination complex, which is non-toxic and can be processed into various forms like capsules or powders.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If the selenium content in organic selenium health products is increased, then the health care effect is improved, but the toxicity increases
Solution Approach 1:
The patent creates a composite structure where selenium forms a coordination complex with tea polyphenol molecules. The selenium atom coordinates with oxygen atoms from the tea polyphenol structure, forming a stable composite material that combines the beneficial effects of both components while reducing toxicity through the chelating effect of tea polyphenol
Solution Approach 2:
The patent changes the chemical parameters of selenium by transforming it from simple inorganic selenium or basic organic selenium compounds into a specific coordination complex with tea polyphenol. This parameter change in molecular structure and chemical bonding state results in altered biological properties, achieving both high selenium content and reduced toxicity
2Reliability
If the selenium content in organic selenium health products is increased, then the disease prevention effect is improved, but the product cannot be fully utilized due to toxicity limitations
Solution Approach 1:
Tea polyphenol acts as an intermediary substance that mediates between selenium and the biological system. The tea polyphenol-selenium coordination complex allows selenium to be delivered at high concentrations while the tea polyphenol component protects against toxicity, enabling full utilization of selenium's disease prevention benefits
3Object-affected harmful factors
If tea polyphenol is used as the base compound, then the nontoxicity and antioxidant activity are maintained, but the selenium content is initially low
Solution Approach 1:
The patent merges tea polyphenol and selenium into a single coordination complex molecule. This merging combines the nontoxic, antioxidant properties of tea polyphenol with the high selenium content requirement, creating a unified compound that exhibits both characteristics simultaneously rather than as separate components
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The selenium-enriched tea polyphenol selenide maintains the original biochemical functions of tea polyphenol while enhancing selenium content and reducing toxicity, making it suitable for health and nutritional products, drugs, and veterinary use, with demonstrated effectiveness in cancer treatment and immune system enhancement.
Implementation Method 1
reacting tea polyphenol with at least one inorganic metallic alkali, to obtain tea polyphenol hydroxy acid salt
Implementation Method 2
reacting the tea polyphenol hydroxy acid salt with SeO2, to obtain the selenium-enriched tea polyphenol selenide
Implementation Method 3
forming a compound with an alkali metal ion and selenium coordination complex
Data Source
AI summary
A selenium-enriched tea polyphenol selenide, has such a structure aswherein R1 is alkali metal ion and selenium coordination complex, and R2═H, orA method for preparing the selenium-enriched tea polyphenol selenide, comprises: A) reacting tea polyphenol with at least one inorganic metallic alkali, to obtain tea polyphenol hydroxy acid salt; and B) reacting the tea polyphenol hydroxy acid salt with SeO2, to obtain the selenium-enriched tea polyphenol selenide.