Self-Expanding Thrombus Extraction for Large-Clot Removal
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Solution Overview
Problem
Current devices and methods for treating venous thrombosis, particularly deep vein thrombosis (DVT), face challenges such as high recurrence rates, inability to handle large clot volumes, and complex treatments involving multiple devices and pharmaceuticals, which can lead to complications like bleeding and increased healthcare costs.
Innovation Solution
A thrombus extraction device with a self-expanding coring element and a braided net structure is designed to core and separate large volumes of thrombus from blood vessels, minimizing the need for pharmaceuticals and reducing recovery time and healthcare costs.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If current devices and methods are used for treating DVT, then treatment can be provided, but high recurrence rates occur and large clot volumes cannot be handled effectively
Solution Approach 1:
The device segments the clot removal process into distinct functional zones: a coring element that mechanically breaks up and cores the thrombus, and an distal filter portion that captures and contains the fragmented clot material. This segmentation allows effective handling of large clot volumes while maintaining reliable prevention of recurrence through complete clot removal and capture
Solution Approach 2:
The coring element extracts and removes the core of the thrombus through mechanical engagement and rotation, physically taking out the bulk of the clot material. The distal filter then extracts and captures any remaining fragmented clot particles, ensuring complete removal and preventing recurrence
2Adaptability or versatility
If multiple treatment devices and pharmaceuticals are used, then comprehensive treatment is achieved, but treatment complexity increases and bleeding risk rises
Solution Approach 1:
The device combines multiple functions into a single universal tool: it can mechanically remove large clot volumes through coring, filter and capture fragmented clot material, and potentially deliver therapeutic agents through the filter structure. This multi-functionality provides comprehensive treatment while eliminating the need for multiple separate devices and pharmaceutical interventions
Solution Approach 2:
The device merges the coring function and filtering function into a single integrated system where the coring element and distal filter work together as one unified device. This merging simplifies the treatment process by replacing multiple separate devices and pharmaceuticals with a single comprehensive mechanical solution
Data Source
AI summary
Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a fenestrated structure, a substantially cylindrical portion formed of a net-like filament mesh structure having a proximal end coupled to a distal end of the fenestrated structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction device by stacking a portion of the net-like filament mesh structure outside of the catheter by distally advancing the self-expanding member until the self-expanding member is beyond a distal end of the catheter; retracting the self-expanding member to unstack the portion of the net-like filament mesh structure and to capture the portion of the thrombus; and withdrawing the thrombus extraction device from the body.